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<StructureSection load='6vqx' size='340' side='right'caption='[[6vqx]], [[Resolution|resolution]] 3.15&Aring;' scene=''>
<StructureSection load='6vqx' size='340' side='right'caption='[[6vqx]], [[Resolution|resolution]] 3.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6vqx]] is a 11 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VQX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6VQX FirstGlance]. <br>
<table><tr><td colspan='2'>[[6vqx]] is a 11 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VQX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6VQX FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6vqx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vqx OCA], [http://pdbe.org/6vqx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6vqx RCSB], [http://www.ebi.ac.uk/pdbsum/6vqx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6vqx ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.15&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6vqx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vqx OCA], [https://pdbe.org/6vqx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6vqx RCSB], [https://www.ebi.ac.uk/pdbsum/6vqx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6vqx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CSY1_PSEAB CSY1_PSEAB]] CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Cas3 and Cascade participate in CRISPR interference, the third stage of CRISPR immunity (Potential). Involved in crRNA production or stability. The Csy ribonucleoprotein complex binds target ssDNA with high affinity but target dsDNA with much lower affinity.<ref>PMID:21398535</ref> <ref>PMID:22522703</ref>  [[http://www.uniprot.org/uniprot/CAS6_PSEAB CAS6_PSEAB]] CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Processes pre-crRNA into individual crRNA units. Absolutely required for crRNA production or stability. Upon expression in E.coli endonucleolytically processes pre-crRNA, although disruption and reconstitution experiments indicate that in situ other genes are also required for processing. Yields 5'-hydroxy and 3'-phosphate groups. The Csy ribonucleoprotein complex binds target ssDNA with high affinity but target dsDNA with much lower affinity.<ref>PMID:20829488</ref> <ref>PMID:21398535</ref> <ref>PMID:22522703</ref> 
[https://www.uniprot.org/uniprot/A0A6B1YCA6_PSEAI A0A6B1YCA6_PSEAI]  
== References ==
 
<references/>
==See Also==
*[[Endonuclease 3D structures|Endonuclease 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Chiu, W]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Huang, Z]]
[[Category: Chiu W]]
[[Category: Li, S]]
[[Category: Huang Z]]
[[Category: Pintilie, G]]
[[Category: Li S]]
[[Category: Zhang, K]]
[[Category: Pintilie G]]
[[Category: Zhu, Y]]
[[Category: Zhang K]]
[[Category: Acrf6]]
[[Category: Zhu Y]]
[[Category: Anti-crispr]]
[[Category: Crispr]]
[[Category: Csy]]
[[Category: Rna binding protein-rna-inhibitor complex]]
[[Category: Type i-f]]

Latest revision as of 17:39, 6 March 2024

Type I-F CRISPR-Csy complex with its inhibitor AcrF6Type I-F CRISPR-Csy complex with its inhibitor AcrF6

Structural highlights

6vqx is a 11 chain structure with sequence from Pseudomonas aeruginosa. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 3.15Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

A0A6B1YCA6_PSEAI

See Also

6vqx, resolution 3.15Å

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