6rin: Difference between revisions

<table><tr><td colspan='2'>[[6rin]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RIN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6RIN FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6rh3|6rh3]], [[6ri7|6ri7]], [[6ri9|6ri9]]</td></tr>

<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">greB, A6581_04870, A6592_17860, A9819_19355, ACN81_28045, AJ318_12850, AM446_03280, AM465_06470, AW059_21840, AW106_06800, AWP75_19390, B1K96_23455, B7C53_02740, B9M99_05190, B9N33_11850, B9T59_15180, BB545_11775, BE963_07880, BEN53_20780, BER14_23830, BIQ87_19125, BIU72_15205, BIZ41_07270, BN17_33411, BTQ04_09175, BTQ06_11100, BWP17_00335, BZL69_06140, C1I57_22680, C2M16_11315, C4K41_11925, C4M78_15275, C5715_11665, C5P43_01370, C5P44_10555, C6986_21785, C6B13_13810, C7B02_12915, C7B06_17550, C7B07_17730, C7B08_15410, CCZ14_09505, CCZ17_12365, CDL37_28230, CIJ94_13670, COD30_08990, COD46_24585, CQP61_02655, CR538_01935, CR539_22285, CRD98_08015, CRE06_04505, CRM83_22430, CRT43_20450, CRT46_19780, CSB64_14420, CT143_16930, CT146_14880, CVH05_26415, CWM24_10205, CXB56_05285, D1900_14635, D2183_13810, D2F89_07605, D3I61_20125, D5F38_05860, D6X47_11590, D7K63_10550, D7Y10_09590, D9D33_12115, D9D43_04330, D9E30_17490, D9E34_05680, D9E35_12335, D9E49_05660, D9F02_06885, D9F12_05730, D9F17_12145, D9F21_10030, D9G11_13190, D9G22_12525, D9G42_17600, D9G48_02635, D9G53_04685, D9H12_12450, D9H53_09445, D9H70_16165, D9H94_02685, D9I20_11335, D9I47_16295, D9I52_07930, D9I82_17890, D9I88_04675, D9J03_03135, D9J39_10095, D9J44_13380, D9J46_06810, D9K10_10415, DD762_12135, DIV22_04250, DL545_02535, DL800_24380, DL925_02870, DLU27_04270, DNQ45_10270, DNR41_15135, DNX30_18525, DOT75_01925, DP258_06460, DQE83_21230, DQF57_08805, DQP22_03685, DS732_24825, DS966_15260, DTL90_06605, DTM10_13330, DTM25_09000, DTM45_15925, DU309_12225, DU321_12435, DU333_19320, EA140_12925, EAI36_16755, EB510_07630, EB553_06270, EB569_05025, EB595_04935, ECs4248, ED060_02600, ED098_03500, ED124_04345, ED287_06925, ED600_01330, ED648_05650, ED653_03405, ED658_07555, ED944_05965, EEO96_14735, EEP03_05760, EF364_04490, EFV06_08470, EGT48_13510, EGY17_06960, EIA08_11750, EIA21_13775, HMPREF3040_00520 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI]), rpoA, pez, phs, sez, b3295, JW3257 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI]), rpoB, groN, nitB, rif, ron, stl, stv, tabD, b3987, JW3950 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI]), rpoC, tabB, b3988, JW3951 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI]), rpoZ, b3649, JW3624 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>

<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] </span></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6rin FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rin OCA], [http://pdbe.org/6rin PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rin RCSB], [http://www.ebi.ac.uk/pdbsum/6rin PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rin ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/RPOC_ECOLI RPOC_ECOLI]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.[HAMAP-Rule:MF_01322] [[http://www.uniprot.org/uniprot/C3SQ22_ECOLX C3SQ22_ECOLX]] Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.[HAMAP-Rule:MF_00930] [[http://www.uniprot.org/uniprot/RPOZ_ECOLI RPOZ_ECOLI]] Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.[HAMAP-Rule:MF_00366] [[http://www.uniprot.org/uniprot/RPOA_ECOLI RPOA_ECOLI]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit plays an important role in subunit assembly since its dimerization is the first step in the sequential assembly of subunits to form the holoenzyme.[HAMAP-Rule:MF_00059] [[http://www.uniprot.org/uniprot/RPOB_ECOLI RPOB_ECOLI]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.[HAMAP-Rule:MF_01321]

[[Category: DNA-directed RNA polymerase]]

[[Category: Ecoli]]

[[Category: Abdelkareem, M]]

[[Category: Crucifix, C]]

[[Category: Guo, X]]

[[Category: Ortiz, J]]

[[Category: Papai, G]]

[[Category: Saint-Andre, C]]

[[Category: Takacs, M]]

[[Category: Weixlbaumer, A]]

[[Category: Transcription]]