2byg: Difference between revisions

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OCA

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 <StructureSection load='2byg' size='340' side='right'caption='[[2byg]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2byg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BYG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BYG FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2byg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BYG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BYG FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2byg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2byg OCA], [http://pdbe.org/2byg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2byg RCSB], [http://www.ebi.ac.uk/pdbsum/2byg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2byg ProSAT]</span></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2byg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2byg OCA], [https://pdbe.org/2byg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2byg RCSB], [https://www.ebi.ac.uk/pdbsum/2byg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2byg ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/DLG2_HUMAN DLG2_HUMAN] Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses (By similarity).
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
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 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
 [[Category: Large Structures]]
-[[Category: Arrowsmith, C]]
+[[Category: Arrowsmith C]]
-[[Category: Berridge, G]]
+[[Category: Berridge G]]
-[[Category: Doyle, D A]]
+[[Category: Doyle DA]]
-[[Category: Edwards, A]]
+[[Category: Edwards A]]
-[[Category: Elkins, J M]]
+[[Category: Elkins JM]]
-[[Category: Structural genomic]]
+[[Category: Salah E]]
-[[Category: Salah, E]]
+[[Category: Schoch GA]]
-[[Category: Schoch, G A]]
+[[Category: Smee CEA]]
-[[Category: Smee, C E.A]]
+[[Category: Sundstrom M]]
-[[Category: Sundstrom, M]]
+[[Category: Weigelt J]]
-[[Category: Weigelt, J]]
-[[Category: Dlg2]]
-[[Category: Pdz]]
-[[Category: Pdz domain]]
-[[Category: Phosphorylation]]
-[[Category: Sgc]]
-[[Category: Sh3 domain]]
-[[Category: Signal transduction]]