4l8u: Difference between revisions

<table><tr><td colspan='2'>[[4l8u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L8U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4L8U FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.01&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9AZ:(2S)-2-[1-AMINO-8-(HYDROXYMETHYL)-9-OXO-9,11-DIHYDROINDOLIZINO[1,2-B]QUINOLIN-7-YL]-2-HYDROXYBUTANOIC+ACID'>9AZ</scene>, <scene name='pdbligand=MYR:MYRISTIC+ACID'>MYR</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4l8u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l8u OCA], [https://pdbe.org/4l8u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4l8u RCSB], [https://www.ebi.ac.uk/pdbsum/4l8u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4l8u ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN] Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:[https://omim.org/entry/103600 103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.<ref>PMID:8048949</ref> <ref>PMID:7852505</ref> <ref>PMID:9329347</ref> <ref>PMID:9589637</ref>  

[https://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.<ref>PMID:19021548</ref>  

[[Category: Carter DC]]

[[Category: Ho JX]]

[[Category: Rose JP]]

[[Category: Ruble J]]

[[Category: Wang Z]]