6tot: Difference between revisions

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 <StructureSection load='6tot' size='340' side='right'caption='[[6tot]], [[Resolution|resolution]] 2.22&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[6tot]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TOT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6TOT FirstGlance]. <br>
+<table><tr><td colspan='2'>[[6tot]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TOT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6TOT FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NRK:(1~{R},2~{S})-2-[(2,4-dimethylpyrimidin-5-yl)oxymethyl]-~{N}-(5-fluoranylpyridin-2-yl)-2-(3-fluorophenyl)cyclopropane-1-carboxamide'>NRK</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGW:(1R)-2-{[(S)-{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(HEXADECANOYLOXY)METHYL]ETHYL+(9Z)-OCTADEC-9-ENOATE'>PGW</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SOG:2-HYDROXYMETHYL-6-OCTYLSULFANYL-TETRAHYDRO-PYRAN-3,4,5-TRIOL'>SOG</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.22&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6tod|6tod]], [[6tos|6tos]], [[6to7|6to7]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NRK:(1~{R},2~{S})-2-[(2,4-dimethylpyrimidin-5-yl)oxymethyl]-~{N}-(5-fluoranylpyridin-2-yl)-2-(3-fluorophenyl)cyclopropane-1-carboxamide'>NRK</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGW:(1R)-2-{[(S)-{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(HEXADECANOYLOXY)METHYL]ETHYL+(9Z)-OCTADEC-9-ENOATE'>PGW</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SOG:2-HYDROXYMETHYL-6-OCTYLSULFANYL-TETRAHYDRO-PYRAN-3,4,5-TRIOL'>SOG</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HCRTR1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6tot FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tot OCA], [https://pdbe.org/6tot PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6tot RCSB], [https://www.ebi.ac.uk/pdbsum/6tot PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6tot ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6tot FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tot OCA], [http://pdbe.org/6tot PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6tot RCSB], [http://www.ebi.ac.uk/pdbsum/6tot PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6tot ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/OX1R_HUMAN OX1R_HUMAN]] Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Seems to be exclusively coupled to the G(q) subclass of heteromeric G proteins, which activates the phospholipase C mediated signaling cascade (By similarity).
+[https://www.uniprot.org/uniprot/OX1R_HUMAN OX1R_HUMAN] Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Seems to be exclusively coupled to the G(q) subclass of heteromeric G proteins, which activates the phospholipase C mediated signaling cascade (By similarity).
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 20: / Line 19: @@
 </div>
 <div class="pdbe-citations 6tot" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Orexin and Orexin receptor|Orexin and Orexin receptor]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
 [[Category: Large Structures]]
-[[Category: Ali, A]]
+[[Category: Ali A]]
-[[Category: Bennett, K A]]
+[[Category: Bennett KA]]
-[[Category: Brown, J D]]
+[[Category: Brown JD]]
-[[Category: Bucknell, S J]]
+[[Category: Bucknell SJ]]
-[[Category: Christopher, J A]]
+[[Category: Christopher JA]]
-[[Category: Congreve, M]]
+[[Category: Congreve M]]
-[[Category: Cooke, R M]]
+[[Category: Cooke RM]]
-[[Category: Cseke, G]]
+[[Category: Cseke G]]
-[[Category: Dore, A S]]
+[[Category: Dore AS]]
-[[Category: Errey, J C]]
+[[Category: Errey JC]]
-[[Category: Graaf, C de]]
+[[Category: Jazayeri A]]
-[[Category: Jazayeri, A]]
+[[Category: Marshall FH]]
-[[Category: Marshall, F H]]
+[[Category: Mason JS]]
-[[Category: Mason, J S]]
+[[Category: Mould R]]
-[[Category: Mould, R]]
+[[Category: Patel JC]]
-[[Category: Patel, J C]]
+[[Category: Rappas M]]
-[[Category: Rappas, M]]
+[[Category: Tehan BG]]
-[[Category: Tehan, B G]]
+[[Category: Weir M]]
-[[Category: Weir, M]]
+[[Category: De Graaf C]]
-[[Category: Gpcr]]
-[[Category: Membrane protein]]