1mg6: Difference between revisions

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<StructureSection load='1mg6' size='340' side='right'caption='[[1mg6]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='1mg6' size='340' side='right'caption='[[1mg6]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1mg6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Deinagkistrodon_acutus Deinagkistrodon acutus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MG6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MG6 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1mg6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Deinagkistrodon_acutus Deinagkistrodon acutus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MG6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MG6 FirstGlance]. <br>
</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phospholipase_A(2) Phospholipase A(2)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.4 3.1.1.4] </span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1mg6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mg6 OCA], [http://pdbe.org/1mg6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1mg6 RCSB], [http://www.ebi.ac.uk/pdbsum/1mg6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1mg6 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mg6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mg6 OCA], [https://pdbe.org/1mg6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mg6 RCSB], [https://www.ebi.ac.uk/pdbsum/1mg6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mg6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PA2H_DEIAC PA2H_DEIAC]] Snake venom phospholipase A2 homolog that shows myotoxic activity. Lacks both catalytic and direct hemolytic activity.  
[https://www.uniprot.org/uniprot/PA2H_DEIAC PA2H_DEIAC] Snake venom phospholipase A2 homolog that shows myotoxic activity. Lacks both catalytic and direct hemolytic activity.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mg/1mg6_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mg/1mg6_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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[[Category: Deinagkistrodon acutus]]
[[Category: Deinagkistrodon acutus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Huang, Q]]
[[Category: Huang Q]]
[[Category: Niu, L]]
[[Category: Niu L]]
[[Category: Teng, M]]
[[Category: Teng M]]
[[Category: Hydrolase]]
[[Category: Pla2]]

Latest revision as of 03:14, 21 November 2024

The Crystal Structure of a K49 PLA2 from the Snake Venom of Agkistrodon acutusThe Crystal Structure of a K49 PLA2 from the Snake Venom of Agkistrodon acutus

Structural highlights

1mg6 is a 1 chain structure with sequence from Deinagkistrodon acutus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.6Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PA2H_DEIAC Snake venom phospholipase A2 homolog that shows myotoxic activity. Lacks both catalytic and direct hemolytic activity.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1mg6, resolution 1.60Å

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