6bgg: Difference between revisions

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 ==Solution NMR structures of the BRD3 ET domain in complex with a CHD4 peptide==
-<StructureSection load='6bgg' size='340' side='right'caption='[[6bgg]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
+<StructureSection load='6bgg' size='340' side='right'caption='[[6bgg]]' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[6bgg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BGG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BGG FirstGlance]. <br>
+<table><tr><td colspan='2'>[[6bgg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BGG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BGG FirstGlance]. <br>
-</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BRD3, KIAA0043, RING3L ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6bgg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bgg OCA], [https://pdbe.org/6bgg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6bgg RCSB], [https://www.ebi.ac.uk/pdbsum/6bgg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6bgg ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bgg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bgg OCA], [http://pdbe.org/6bgg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bgg RCSB], [http://www.ebi.ac.uk/pdbsum/6bgg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bgg ProSAT]</span></td></tr>
 </table>
-== Disease ==
-[[http://www.uniprot.org/uniprot/BRD3_HUMAN BRD3_HUMAN]] Note=A chromosomal aberration involving BRD3 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;9)(q14;q34) with NUT which produces a BRD3-NUT fusion protein.
 == Function ==
-[[http://www.uniprot.org/uniprot/BRD3_HUMAN BRD3_HUMAN]] Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling and interaction with transcription factors. Regulates transcription by promoting the binding of the transcription factor GATA1 to its targets (By similarity). Regulates transcription of the CCND1 gene.<ref>PMID:18406326</ref>
+[https://www.uniprot.org/uniprot/CHD4_HUMAN CHD4_HUMAN] Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones.<ref>PMID:9804427</ref> <ref>PMID:17626165</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 27: / Line 24: @@
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
 [[Category: Large Structures]]
-[[Category: Blobel, G A]]
+[[Category: Blobel GA]]
-[[Category: Campbell, A E]]
+[[Category: Campbell AE]]
-[[Category: Gamsjaeger, R]]
+[[Category: Gamsjaeger R]]
-[[Category: Kwan, A H]]
+[[Category: Kwan AH]]
-[[Category: Kwong, C]]
+[[Category: Kwong C]]
-[[Category: Low, J K.K]]
+[[Category: Low JKK]]
-[[Category: Lu, B]]
+[[Category: Lu B]]
-[[Category: Mackay, J P]]
+[[Category: Mackay JP]]
-[[Category: Silva, A P.G]]
+[[Category: Silva APG]]
-[[Category: Szyszka, T N]]
+[[Category: Szyszka TN]]
-[[Category: Vakoc, C R]]
+[[Category: Vakoc CR]]
-[[Category: Wai, D C.C]]
+[[Category: Wai DCC]]
-[[Category: Wilkinson-White, L]]
+[[Category: Wilkinson-White L]]
-[[Category: Epigenetic]]
-[[Category: Protein binding]]
-[[Category: Transcription regulation]]