6dge: Difference between revisions

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<StructureSection load='6dge' size='340' side='right'caption='[[6dge]], [[Resolution|resolution]] 1.91&Aring;' scene=''>
<StructureSection load='6dge' size='340' side='right'caption='[[6dge]], [[Resolution|resolution]] 1.91&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6dge]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DGE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DGE FirstGlance]. <br>
<table><tr><td colspan='2'>[[6dge]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DGE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6DGE FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GBG:N~6~-[(1E)-2-chloroethanimidoyl]-L-lysine'>GBG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.91&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3i2e|3i2e]], [[3p8e|3p8e]], [[3i4a|3i4a]], [[3p8p|3p8p]], [[2jai|2jai]], [[2jaj|2jaj]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GBG:N~6~-[(1E)-2-chloroethanimidoyl]-L-lysine'>GBG</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DDAH1, DDAH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6dge FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dge OCA], [https://pdbe.org/6dge PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6dge RCSB], [https://www.ebi.ac.uk/pdbsum/6dge PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6dge ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dimethylargininase Dimethylargininase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.3.18 3.5.3.18] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dge FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dge OCA], [http://pdbe.org/6dge PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dge RCSB], [http://www.ebi.ac.uk/pdbsum/6dge PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dge ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DDAH1_HUMAN DDAH1_HUMAN]] Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.  
[https://www.uniprot.org/uniprot/DDAH1_HUMAN DDAH1_HUMAN] Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
<div class="pdbe-citations 6dge" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6dge" style="background-color:#fffaf0;"></div>
==See Also==
*[[Dimethylarginine Dimethylaminohydrolase|Dimethylarginine Dimethylaminohydrolase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Dimethylargininase]]
[[Category: Homo sapiens]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Burstein-Teitelbaum, G]]
[[Category: Burstein-Teitelbaum G]]
[[Category: Er, J A.V]]
[[Category: Er JAV]]
[[Category: Fast, W]]
[[Category: Fast W]]
[[Category: Monzingo, A F]]
[[Category: Monzingo AF]]
[[Category: Tuley, A]]
[[Category: Tuley A]]
[[Category: Covalent inhibitor]]
[[Category: Enzyme adduct]]
[[Category: Hydrolase]]
[[Category: Hydrolase-hydrolase inhibitor complex]]

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