4ztv: Difference between revisions

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<StructureSection load='4ztv' size='340' side='right'caption='[[4ztv]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
<StructureSection load='4ztv' size='340' side='right'caption='[[4ztv]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ztv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycta Mycta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZTV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZTV FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ztv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Ra Mycobacterium tuberculosis H37Ra]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZTV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZTV FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TA7:4,4,4-TRIFLUORO-1-(4-METHOXYPHENYL)BUTANE-1,3-DIONE'>TA7</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.01&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3qsa|3qsa]], [[3qr9|3qr9]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TA7:4,4,4-TRIFLUORO-1-(4-METHOXYPHENYL)BUTANE-1,3-DIONE'>TA7</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trpD, MRA_2208 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=419947 MYCTA])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ztv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ztv OCA], [https://pdbe.org/4ztv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ztv RCSB], [https://www.ebi.ac.uk/pdbsum/4ztv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ztv ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Anthranilate_phosphoribosyltransferase Anthranilate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.18 2.4.2.18] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ztv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ztv OCA], [http://pdbe.org/4ztv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ztv RCSB], [http://www.ebi.ac.uk/pdbsum/4ztv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ztv ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/TRPD_MYCTA TRPD_MYCTA]] Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).  
[https://www.uniprot.org/uniprot/TRPD_MYCTA TRPD_MYCTA] Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).


==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Anthranilate phosphoribosyltransferase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Mycta]]
[[Category: Mycobacterium tuberculosis H37Ra]]
[[Category: Baker, E N]]
[[Category: Baker EN]]
[[Category: Eom, J]]
[[Category: Eom J]]
[[Category: Evans, G L]]
[[Category: Evans GL]]
[[Category: Lott, J S]]
[[Category: Lott JS]]
[[Category: Structural genomic]]
[[Category: Anprt]]
[[Category: Non-anthranilate-like inhibitor]]
[[Category: Tbsgc]]
[[Category: Transferase-transferase inhibitor complex]]
[[Category: Trpd]]

Latest revision as of 11:24, 27 September 2023

Non-anthranilate-like inhibitor (TAMU-A7) complexed with anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis in absence of PRPPNon-anthranilate-like inhibitor (TAMU-A7) complexed with anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis in absence of PRPP

Structural highlights

4ztv is a 2 chain structure with sequence from Mycobacterium tuberculosis H37Ra. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.01Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

TRPD_MYCTA Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).

See Also

4ztv, resolution 2.01Å

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