6tpn: Difference between revisions

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<StructureSection load='6tpn' size='340' side='right'caption='[[6tpn]], [[Resolution|resolution]] 2.61&Aring;' scene=''>
<StructureSection load='6tpn' size='340' side='right'caption='[[6tpn]], [[Resolution|resolution]] 2.61&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6tpn]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TPN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6TPN FirstGlance]. <br>
<table><tr><td colspan='2'>[[6tpn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Pyrococcus_abyssi_GE5 Pyrococcus abyssi GE5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TPN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6TPN FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=NU8:2-(5,6-dimethoxypyridin-3-yl)-1,1-bis(oxidanylidene)-4-[[2,4,6-tris(fluoranyl)phenyl]methyl]pyrido[2,3-e][1,2,4]thiadiazin-3-one'>NU8</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.608&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=YCM:S-(2-AMINO-2-OXOETHYL)-L-CYSTEINE'>YCM</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=NU8:2-(5,6-dimethoxypyridin-3-yl)-1,1-bis(oxidanylidene)-4-[[2,4,6-tris(fluoranyl)phenyl]methyl]pyrido[2,3-e][1,2,4]thiadiazin-3-one'>NU8</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=YCM:S-(2-AMINO-2-OXOETHYL)-L-CYSTEINE'>YCM</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6tpn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tpn OCA], [http://pdbe.org/6tpn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6tpn RCSB], [http://www.ebi.ac.uk/pdbsum/6tpn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6tpn ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6tpn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tpn OCA], [https://pdbe.org/6tpn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6tpn RCSB], [https://www.ebi.ac.uk/pdbsum/6tpn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6tpn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/OX2R_HUMAN OX2R_HUMAN]] Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides.  
[https://www.uniprot.org/uniprot/Q9V2J8_PYRAB Q9V2J8_PYRAB] [https://www.uniprot.org/uniprot/OX2R_HUMAN OX2R_HUMAN] Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6tpn" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6tpn" style="background-color:#fffaf0;"></div>
==See Also==
*[[Orexin and Orexin receptor|Orexin and Orexin receptor]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Ali, A]]
[[Category: Pyrococcus abyssi GE5]]
[[Category: Bennett, K A]]
[[Category: Ali A]]
[[Category: Brown, J D]]
[[Category: Bennett KA]]
[[Category: Bucknell, S J]]
[[Category: Brown JD]]
[[Category: Christopher, J A]]
[[Category: Bucknell SJ]]
[[Category: Congreve, M]]
[[Category: Christopher JA]]
[[Category: Cooke, R M]]
[[Category: Congreve M]]
[[Category: Cseke, G]]
[[Category: Cooke RM]]
[[Category: Dore, A S]]
[[Category: Cseke G]]
[[Category: Errey, J C]]
[[Category: Dore AS]]
[[Category: Graaf, C de]]
[[Category: Errey JC]]
[[Category: Jazayeri, A]]
[[Category: Jazayeri A]]
[[Category: Marshall, F H]]
[[Category: Marshall FH]]
[[Category: Mason, J S]]
[[Category: Mason JS]]
[[Category: Mould, R]]
[[Category: Mould R]]
[[Category: Patel, J C]]
[[Category: Patel JC]]
[[Category: Rappas, M]]
[[Category: Rappas M]]
[[Category: Tehan, B G]]
[[Category: Tehan BG]]
[[Category: Weir, M]]
[[Category: Weir M]]
[[Category: Gpcr]]
[[Category: De Graaf C]]
[[Category: Membrane protein]]

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