1u9b: Difference between revisions
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<StructureSection load='1u9b' size='340' side='right'caption='[[1u9b]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='1u9b' size='340' side='right'caption='[[1u9b]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1u9b]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[1u9b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U9B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U9B FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u9b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u9b OCA], [https://pdbe.org/1u9b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u9b RCSB], [https://www.ebi.ac.uk/pdbsum/1u9b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u9b ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/UBC9_MOUSE UBC9_MOUSE] Accepts the ubiquitin-like proteins SUMO1, SUMO2 and SUMO3 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2 or CBX4. Can catalyze the formation of poly-SUMO chains. Essential for nuclear architecture, chromosome segregation and embryonic viability. Necessary for sumoylation of FOXL2 and KAT5 (By similarity).<ref>PMID:16326389</ref> <ref>PMID:17187077</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mus musculus]] | ||
[[Category: Bernards R]] | |||
[[Category: Bernards | [[Category: Hateboer G]] | ||
[[Category: Hateboer | [[Category: Perrakis A]] | ||
[[Category: Perrakis | [[Category: Sixma TK]] | ||
[[Category: Sixma | [[Category: Tong H]] | ||
[[Category: Tong | |||