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| ==Structure of Vaccinia Virus DNA-dependent RNA polymerase elongation complex== | | ==Structure of Vaccinia Virus DNA-dependent RNA polymerase elongation complex== |
| <StructureSection load='6rid' size='340' side='right'caption='[[6rid]], [[Resolution|resolution]] 2.90Å' scene=''> | | <SX load='6rid' size='340' side='right' viewer='molstar' caption='[[6rid]], [[Resolution|resolution]] 2.90Å' scene=''> |
| == Structural highlights == | | == Structural highlights == |
| <table><tr><td colspan='2'>[[6rid]] is a 11 chain structure with sequence from [http://en.wikipedia.org/wiki/Vaccinia_virus_glv-1h68 Vaccinia virus glv-1h68]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RID OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6RID FirstGlance]. <br> | | <table><tr><td colspan='2'>[[6rid]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus] and [https://en.wikipedia.org/wiki/Vaccinia_virus_GLV-1h68 Vaccinia virus GLV-1h68]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RID OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6RID FirstGlance]. <br> |
| </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.9Å</td></tr> |
| <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6rfg|6rfg]], [[6rfl|6rfl]], [[6rie|6rie]]</td></tr>
| | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GL125 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=502057 Vaccinia virus GLV-1h68]), GL194 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=502057 Vaccinia virus GLV-1h68]), GL205 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=502057 Vaccinia virus GLV-1h68]), GL123 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=502057 Vaccinia virus GLV-1h68]), GL167 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=502057 Vaccinia virus GLV-1h68]), GL147 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=502057 Vaccinia virus GLV-1h68]), GL107 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=502057 Vaccinia virus GLV-1h68]), GL076 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=502057 Vaccinia virus GLV-1h68])</td></tr> | | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6rid FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rid OCA], [https://pdbe.org/6rid PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6rid RCSB], [https://www.ebi.ac.uk/pdbsum/6rid PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6rid ProSAT]</span></td></tr> |
| <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] </span></td></tr>
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| <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6rid FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rid OCA], [http://pdbe.org/6rid PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rid RCSB], [http://www.ebi.ac.uk/pdbsum/6rid PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rid ProSAT]</span></td></tr> | |
| </table> | | </table> |
| == Function ==
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| [[http://www.uniprot.org/uniprot/B9U1R2_9POXV B9U1R2_9POXV]] Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates. Responsible for the transcription of early, intermediate and late genes.[PIRNR:PIRNR000746] [[http://www.uniprot.org/uniprot/B9U1I0_9POXV B9U1I0_9POXV]] Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates. Responsible for the transcription of early, intermediate and late genes.[PIRNR:PIRNR000744] [[http://www.uniprot.org/uniprot/B9U1M4_9POXV B9U1M4_9POXV]] Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates. Responsible for the transcription of early, intermediate and late genes.[PIRNR:PIRNR000743]
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| <div style="background-color:#fffaf0;"> | | <div style="background-color:#fffaf0;"> |
| == Publication Abstract from PubMed == | | == Publication Abstract from PubMed == |
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| </div> | | </div> |
| <div class="pdbe-citations 6rid" style="background-color:#fffaf0;"></div> | | <div class="pdbe-citations 6rid" style="background-color:#fffaf0;"></div> |
| | |
| | ==See Also== |
| | *[[RNA polymerase 3D structures|RNA polymerase 3D structures]] |
| == References == | | == References == |
| <references/> | | <references/> |
| __TOC__ | | __TOC__ |
| </StructureSection> | | </SX> |
| [[Category: DNA-directed RNA polymerase]]
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| [[Category: Large Structures]] | | [[Category: Large Structures]] |
| [[Category: Vaccinia virus glv-1h68]] | | [[Category: Vaccinia virus]] |
| [[Category: Bartuli, J]] | | [[Category: Vaccinia virus GLV-1h68]] |
| [[Category: Bedenk, K]] | | [[Category: Bartuli J]] |
| [[Category: Cramer, P]] | | [[Category: Bedenk K]] |
| [[Category: Dienemann, C]] | | [[Category: Cramer P]] |
| [[Category: Fischer, U]] | | [[Category: Dienemann C]] |
| [[Category: Grimm, C]] | | [[Category: Fischer U]] |
| [[Category: Hillen, H S]] | | [[Category: Grimm C]] |
| [[Category: Szalar, A]] | | [[Category: Hillen HS]] |
| [[Category: Gene expression]]
| | [[Category: Szalar A]] |
| [[Category: Rna polymerase]]
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| [[Category: Transcription]]
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| [[Category: Vaccinia]]
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| [[Category: Viral protein]]
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