5fff: Difference between revisions

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<StructureSection load='5fff' size='340' side='right'caption='[[5fff]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='5fff' size='340' side='right'caption='[[5fff]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5fff]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Daffodil Daffodil]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FFF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FFF FirstGlance]. <br>
<table><tr><td colspan='2'>[[5fff]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Narcissus_pseudonarcissus Narcissus pseudonarcissus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FFF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FFF FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5XC:1,3-BENZODIOXOLE-5-CARBALDEHYDE'>5XC</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.501&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5feu|5feu]], [[5ff9|5ff9]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5XC:1,3-BENZODIOXOLE-5-CARBALDEHYDE'>5XC</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fff FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fff OCA], [http://pdbe.org/5fff PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fff RCSB], [http://www.ebi.ac.uk/pdbsum/5fff PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fff ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fff FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fff OCA], [https://pdbe.org/5fff PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fff RCSB], [https://www.ebi.ac.uk/pdbsum/5fff PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fff ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NR_NARPS NR_NARPS] In the Amaryllidaceae alkaloids biosynthesic pathway, catalyzes the conversion of noroxomaritidine to oxomaritidine, a precursor of haemanthamine- and crinamine-type alkaloids, promising anticancer agents (PubMed:27252378). Can also, to some extent, catalyze the condensation of 3,4-dihydroxybenzaldehyde (3,4-DHBA) and tyramine to produce norbelladine, and of isovanillin and tyramine to produce 4'-O-methylnorbelladine (PubMed:27252378).<ref>PMID:27252378</ref>
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Daffodil]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Holland, C K]]
[[Category: Narcissus pseudonarcissus]]
[[Category: Jez, J M]]
[[Category: Holland CK]]
[[Category: Oxidoreductase]]
[[Category: Jez JM]]
[[Category: Short-chain dehydrogenase/reductase alkaloid biosynthesis]]

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