1sn4: Difference between revisions

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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 <StructureSection load='1sn4' size='340' side='right'caption='[[1sn4]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1sn4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mesobuthus_martensii Mesobuthus martensii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SN4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1SN4 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1sn4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mesobuthus_martensii Mesobuthus martensii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SN4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SN4 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1sn1|1sn1]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sn4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sn4 OCA], [http://pdbe.org/1sn4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1sn4 RCSB], [http://www.ebi.ac.uk/pdbsum/1sn4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1sn4 ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sn4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sn4 OCA], [https://pdbe.org/1sn4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sn4 RCSB], [https://www.ebi.ac.uk/pdbsum/1sn4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sn4 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/SCX9_MESMA SCX9_MESMA]] Binds to sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal transmission. This toxin is active against mammals.
+[https://www.uniprot.org/uniprot/SCX4_MESMA SCX4_MESMA] Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission. This toxin is active against mammals.
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
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    <jmolCheckbox>
      <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sn/1sn4_consurf.spt"</scriptWhenChecked>
-     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
@@ Line 35: / Line 35: @@
 [[Category: Large Structures]]
 [[Category: Mesobuthus martensii]]
-[[Category: He, X L]]
+[[Category: He XL]]
-[[Category: Li, H M]]
+[[Category: Li HM]]
-[[Category: Liu, X Q]]
+[[Category: Liu XQ]]
-[[Category: Wang, D C]]
+[[Category: Wang DC]]
-[[Category: Zeng, Z H]]
+[[Category: Zeng ZH]]
-[[Category: Neurotoxin]]
-[[Category: Scorpion]]
-[[Category: Sodium channel inhibitor]]
-[[Category: Toxin]]