2vph: Difference between revisions

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<StructureSection load='2vph' size='340' side='right'caption='[[2vph]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='2vph' size='340' side='right'caption='[[2vph]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2vph]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VPH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VPH FirstGlance]. <br>
<table><tr><td colspan='2'>[[2vph]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VPH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VPH FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2cs5|2cs5]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vph FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vph OCA], [https://pdbe.org/2vph PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vph RCSB], [https://www.ebi.ac.uk/pdbsum/2vph PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vph ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vph FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vph OCA], [http://pdbe.org/2vph PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vph RCSB], [http://www.ebi.ac.uk/pdbsum/2vph PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vph ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PTN4_HUMAN PTN4_HUMAN] May act at junctions between the membrane and the cytoskeleton.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Tyrosine phosphatase|Tyrosine phosphatase]]
*[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Protein-tyrosine-phosphatase]]
[[Category: Arrowsmith CH]]
[[Category: Arrowsmith, C H]]
[[Category: Bountra C]]
[[Category: Bountra, C]]
[[Category: Burgess-Brown N]]
[[Category: Burgess-Brown, N]]
[[Category: Edwards A]]
[[Category: Delft, F von]]
[[Category: Elkins JM]]
[[Category: Edwards, A]]
[[Category: Filippakopoulos P]]
[[Category: Elkins, J M]]
[[Category: Kavanagh K]]
[[Category: Filippakopoulos, P]]
[[Category: Knapp S]]
[[Category: Kavanagh, K]]
[[Category: Pike ACW]]
[[Category: Knapp, S]]
[[Category: Roos AK]]
[[Category: Pike, A C.W]]
[[Category: Wang J]]
[[Category: Roos, A K]]
[[Category: Weigelt J]]
[[Category: Wang, J]]
[[Category: Von Delft F]]
[[Category: Weigelt, J]]
[[Category: Cytoskeleton]]
[[Category: Dephosphorylation]]
[[Category: Hydrolase]]
[[Category: Megakaryocyte]]
[[Category: Protein phosphatase]]
[[Category: Ptpmeg]]
[[Category: Ptpn4]]
[[Category: Structural protein]]

Latest revision as of 18:27, 13 December 2023

Crystal structure of the human protein tyrosine phosphatase, non- receptor type 4, PDZ domainCrystal structure of the human protein tyrosine phosphatase, non- receptor type 4, PDZ domain

Structural highlights

2vph is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.9Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PTN4_HUMAN May act at junctions between the membrane and the cytoskeleton.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2vph, resolution 1.90Å

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OCA