6uzd: Difference between revisions

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-'''Unreleased structure'''
-The entry 6uzd is ON HOLD
+==Anthrax toxin protective antigen channels bound to edema factor==
+<SX load='6uzd' size='340' side='right' viewer='molstar' caption='[[6uzd]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6uzd]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UZD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6UZD FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.4&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6uzd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6uzd OCA], [https://pdbe.org/6uzd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6uzd RCSB], [https://www.ebi.ac.uk/pdbsum/6uzd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6uzd ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/CYAA_BACAN CYAA_BACAN] One of the three proteins composing the anthrax toxin, the agent which infects many mammalian species and that may cause death. EF is a calmodulin-dependent adenylyl cyclase that, when associated with PA, causes edema. EF is not toxic by itself and it is required for the survival of germinated spores within macrophages at the early stages of infection. Provokes dramatic elevation of intracellular cAMP levels in the host.
-Authors:
+==See Also==
+*[[3D Adenylyl cyclase 3D structures|3D Adenylyl cyclase 3D structures]]
-Description:
+__TOC__
-[[Category: Unreleased Structures]]
+</SX>
+[[Category: Bacillus anthracis]]
+[[Category: Large Structures]]
+[[Category: Hardenbrook NJ]]
+[[Category: Krantz BA]]
+[[Category: Liu S]]
+[[Category: Zhou K]]
+[[Category: Zhou ZH]]