6utj: Difference between revisions

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'''Unreleased structure'''


The entry 6utj is ON HOLD
==Allosteric couple between alpha rings of the 20S proteasome. 20S proteasome singly capped by PA26/E102A, C-terminus replaced by PAN C-terminus==
<StructureSection load='6utj' size='340' side='right'caption='[[6utj]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6utj]] is a 35 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermoplasma_acidophilum Thermoplasma acidophilum] and [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UTJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6UTJ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6utj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6utj OCA], [https://pdbe.org/6utj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6utj RCSB], [https://www.ebi.ac.uk/pdbsum/6utj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6utj ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PSA_THEAC PSA_THEAC] Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. The T.acidophilum proteasome is able to cleave oligopeptides after Tyr, Leu, Phe, and to a lesser extent after Glu and Arg. Thus, displays chymotrypsin-like activity and low level of caspase-like and trypsin-like activities.<ref>PMID:8999862</ref>


Authors: Cheng, Y., Yu, Z.
==See Also==
 
*[[Proteasome 3D structures|Proteasome 3D structures]]
Description: Allosteric couple between alpha rings of the 20S proteasome. 20S proteasome singly capped by PA26/E102A, C-terminus replaced by PAN C-terminus
== References ==
[[Category: Unreleased Structures]]
<references/>
[[Category: Cheng, Y]]
__TOC__
[[Category: Yu, Z]]
</StructureSection>
[[Category: Large Structures]]
[[Category: Thermoplasma acidophilum]]
[[Category: Trypanosoma brucei]]
[[Category: Cheng Y]]
[[Category: Yu Z]]

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