1ipb: Difference between revisions

<table><tr><td colspan='2'>[[1ipb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IPB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IPB FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTA:P1-7-METHYLGUANOSINE-P3-ADENOSINE-5,5-TRIPHOSPHATE'>GTA</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ipb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ipb OCA], [https://pdbe.org/1ipb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ipb RCSB], [https://www.ebi.ac.uk/pdbsum/1ipb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ipb ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/IF4E_HUMAN IF4E_HUMAN] Its translation stimulation activity is repressed by binding to the complex CYFIP1-FMR1 (By similarity). Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.<ref>PMID:16271312</ref>  

[[Category: Homo sapiens]]

[[Category: Fukuhara S]]

[[Category: Hasegawa H]]

[[Category: Ishida T]]

[[Category: Ishikawa M]]

[[Category: Katsuya Y]]

[[Category: Kitamura K]]

[[Category: Miura K]]

[[Category: Miyoshi H]]

[[Category: Morino S]]

[[Category: Nozoe Y]]

[[Category: Okabe K]]

[[Category: Sasaki M]]

[[Category: Shen X]]

[[Category: Taniguchi T]]

[[Category: Terashima A]]

[[Category: Tomoo K]]