1iv2: Difference between revisions
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<StructureSection load='1iv2' size='340' side='right'caption='[[1iv2]], [[Resolution|resolution]] 1.55Å' scene=''> | <StructureSection load='1iv2' size='340' side='right'caption='[[1iv2]], [[Resolution|resolution]] 1.55Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1iv2]] is a 6 chain structure with sequence from [ | <table><tr><td colspan='2'>[[1iv2]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IV2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IV2 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CDP:CYTIDINE-5-DIPHOSPHATE'>CDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1iv2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iv2 OCA], [https://pdbe.org/1iv2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1iv2 RCSB], [https://www.ebi.ac.uk/pdbsum/1iv2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1iv2 ProSAT], [https://www.topsan.org/Proteins/RSGI/1iv2 TOPSAN]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/ISPF_THET8 ISPF_THET8] Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).<ref>PMID:12499535</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Kishida | [[Category: Thermus thermophilus]] | ||
[[Category: Kuzuyama | [[Category: Kishida H]] | ||
[[Category: Park | [[Category: Kuzuyama T]] | ||
[[Category: Park S-Y]] | |||
[[Category: Sirouzu | [[Category: Sirouzu M]] | ||
[[Category: Tame | [[Category: Tame JRH]] | ||
[[Category: Terada | [[Category: Terada T]] | ||
[[Category: Unzai | [[Category: Unzai S]] | ||
[[Category: Wada | [[Category: Wada T]] | ||
[[Category: Yokoyama | [[Category: Yokoyama S]] | ||