6t27: Difference between revisions

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-'''Unreleased structure'''
-The entry 6t27 is ON HOLD  until Paper Publication
+==Structure of Human Aldose Reductase Mutant L301A with a Citrate Molecule Bound in the Anion Binding Pocket==
+<StructureSection load='6t27' size='340' side='right'caption='[[6t27]], [[Resolution|resolution]] 1.11&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6t27]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6T27 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6T27 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.11&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6t27 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6t27 OCA], [https://pdbe.org/6t27 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6t27 RCSB], [https://www.ebi.ac.uk/pdbsum/6t27 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6t27 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ALDR_HUMAN ALDR_HUMAN] Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
-Authors: Hubert, L.-S., Ley, M., Heine, A., Klebe, G.
+==See Also==
+*[[Aldose reductase 3D structures|Aldose reductase 3D structures]]
-Description: Structure of Human Aldose Reductase Mutant L301A with a Citrate Molecule Bound in the Anion Binding Pocket
+__TOC__
-[[Category: Unreleased Structures]]
+</StructureSection>
-[[Category: Ley, M]]
+[[Category: Homo sapiens]]
-[[Category: Heine, A]]
+[[Category: Large Structures]]
-[[Category: Hubert, L.-S]]
+[[Category: Heine A]]
-[[Category: Klebe, G]]
+[[Category: Hubert L-S]]
+[[Category: Klebe G]]
+[[Category: Ley M]]