6ul7: Difference between revisions
New page: '''Unreleased structure''' The entry 6ul7 is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures |
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==Structure of human ketohexokinase-C in complex with fructose, NO3, and osthole== | |||
<StructureSection load='6ul7' size='340' side='right'caption='[[6ul7]], [[Resolution|resolution]] 2.30Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6ul7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UL7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6UL7 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A0O:7-methoxy-8-(3-methylbut-2-enyl)chromen-2-one'>A0O</scene>, <scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ul7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ul7 OCA], [https://pdbe.org/6ul7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ul7 RCSB], [https://www.ebi.ac.uk/pdbsum/6ul7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ul7 ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/KHK_HUMAN KHK_HUMAN] Defects in KHK are the cause of fructosuria (FRUCT) [MIM:[https://omim.org/entry/229800 229800]. Benign defect of intermediary metabolism.<ref>PMID:19237742</ref> <ref>PMID:7833921</ref> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/KHK_HUMAN KHK_HUMAN] | |||
==See Also== | |||
*[[Ketohexokinase|Ketohexokinase]] | |||
== References == | |||
[[Category: | <references/> | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Allen KN]] | |||
[[Category: Gardner S]] | |||
[[Category: Gasper WC]] | |||
[[Category: Tolan DR]] |