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<StructureSection load='2a64' size='340' side='right'caption='[[2a64]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
<StructureSection load='2a64' size='340' side='right'caption='[[2a64]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2a64]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A64 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2A64 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2a64]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A64 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A64 FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2a64 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a64 OCA], [http://pdbe.org/2a64 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2a64 RCSB], [http://www.ebi.ac.uk/pdbsum/2a64 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2a64 ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a64 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a64 OCA], [https://pdbe.org/2a64 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a64 RCSB], [https://www.ebi.ac.uk/pdbsum/2a64 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a64 ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
The x-ray crystal structure of a 417-nt ribonuclease P RNA from Bacillus stearothermophilus was solved to 3.3-A resolution. This RNA enzyme is constructed from a number of coaxially stacked helical domains joined together by local and long-range interactions. These helical domains are arranged to form a remarkably flat surface, which is implicated by a wealth of biochemical data in the binding and cleavage of the precursors of transfer RNA substrate. Previous photoaffinity crosslinking data are used to position the substrate on the crystal structure and to identify the chemically active site of the ribozyme. This site is located in a highly conserved core structure formed by intricately interlaced long-range interactions between interhelical sequences.
Crystal structure of a bacterial ribonuclease P RNA.,Kazantsev AV, Krivenko AA, Harrington DJ, Holbrook SR, Adams PD, Pace NR Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13392-7. Epub 2005 Sep 12. PMID:16157868<ref>PMID:16157868</ref>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 2a64" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Ribonuclease|Ribonuclease]]
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
*[[Temp|Temp]]
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Geobacillus stearothermophilus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Adams, P D]]
[[Category: Adams PD]]
[[Category: Harrington, D J]]
[[Category: Harrington DJ]]
[[Category: Holbrook, S R]]
[[Category: Holbrook SR]]
[[Category: Kazantsev, A V]]
[[Category: Kazantsev AV]]
[[Category: Krivenko, A A]]
[[Category: Krivenko AA]]
[[Category: Pace, N R]]
[[Category: Pace NR]]
[[Category: Hydrolase]]
[[Category: Ribonuclease]]
[[Category: Ribozyme]]
[[Category: Rna]]

Latest revision as of 12:11, 14 February 2024

Crystal Structure of Bacterial Ribonuclease P RNACrystal Structure of Bacterial Ribonuclease P RNA

Structural highlights

2a64 is a 1 chain structure with sequence from Geobacillus stearothermophilus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3.3Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

See Also

2a64, resolution 3.30Å

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