6bus: Difference between revisions

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<StructureSection load='6bus' size='340' side='right'caption='[[6bus]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='6bus' size='340' side='right'caption='[[6bus]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6bus]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BUS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BUS FirstGlance]. <br>
<table><tr><td colspan='2'>[[6bus]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Deltapapillomavirus_4 Deltapapillomavirus 4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BUS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BUS FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bus FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bus OCA], [http://pdbe.org/6bus PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bus RCSB], [http://www.ebi.ac.uk/pdbsum/6bus PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bus ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6bus FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bus OCA], [https://pdbe.org/6bus PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6bus RCSB], [https://www.ebi.ac.uk/pdbsum/6bus PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6bus ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/VE2_BPV1 VE2_BPV1]] E2 regulates viral transcription and DNA replication. Binds to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory region. Can either activate or repress transcription depending on E2RE's position with regards to proximal promoter elements. Repression occurs by sterically hindering the assembly of the transcription initiation complex. The E1-E2 complex binds to the origin of DNA replication.  
[https://www.uniprot.org/uniprot/VE2_BPV1 VE2_BPV1] E2 regulates viral transcription and DNA replication. Binds to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory region. Can either activate or repress transcription depending on E2RE's position with regards to proximal promoter elements. Repression occurs by sterically hindering the assembly of the transcription initiation complex. The E1-E2 complex binds to the origin of DNA replication.
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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<div class="pdbe-citations 6bus" style="background-color:#fffaf0;"></div>
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==See Also==
*[[Regulatory protein E2|Regulatory protein E2]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Deltapapillomavirus 4]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Barbosa, J A.R G]]
[[Category: Barbosa JARG]]
[[Category: Leroy, L M.D]]
[[Category: Leroy LMD]]
[[Category: Pinheiro, C B]]
[[Category: Pinheiro CB]]
[[Category: Polikarpov, I]]
[[Category: Polikarpov I]]
[[Category: Bpv-1]]
[[Category: Dna binding protein]]
[[Category: E2]]
[[Category: Open reading frame]]

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