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<StructureSection load='2iwz' size='340' side='right'caption='[[2iwz]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
<StructureSection load='2iwz' size='340' side='right'caption='[[2iwz]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2iwz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IWZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IWZ FirstGlance]. <br>
<table><tr><td colspan='2'>[[2iwz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IWZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IWZ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6NA:HEXANOIC+ACID'>6NA</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2c9h|2c9h]], [[2iwy|2iwy]], [[2ix4|2ix4]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6NA:HEXANOIC+ACID'>6NA</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-ketoacyl-[acyl-carrier-protein]_synthase_I Beta-ketoacyl-[acyl-carrier-protein] synthase I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.41 2.3.1.41] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iwz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iwz OCA], [https://pdbe.org/2iwz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iwz RCSB], [https://www.ebi.ac.uk/pdbsum/2iwz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iwz ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iwz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iwz OCA], [http://pdbe.org/2iwz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2iwz RCSB], [http://www.ebi.ac.uk/pdbsum/2iwz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2iwz ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/OXSM_HUMAN OXSM_HUMAN] May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function.<ref>PMID:15668256</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Christensen, C E]]
[[Category: Christensen CE]]
[[Category: Henriksen, A]]
[[Category: Henriksen A]]
[[Category: Kragelund, B B]]
[[Category: Kragelund BB]]
[[Category: Wettstein-Knowles, P von]]
[[Category: Von Wettstein-Knowles P]]
[[Category: Acyltransferase]]
[[Category: Beta-ketoacyl acp synthase]]
[[Category: Cerulenin]]
[[Category: Claisen condensation]]
[[Category: Fatty acid biosynthesis]]
[[Category: Fatty acid synthesis]]
[[Category: Homo sapien]]
[[Category: Ka]]
[[Category: Lipid synthesis]]
[[Category: Mitochondria]]
[[Category: Mitochondrion]]
[[Category: Transferase]]
[[Category: Transit peptide]]

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