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==Solution structure of the lambda integrase amino-terminal domain==
==Solution structure of the lambda integrase amino-terminal domain==
<StructureSection load='1kjk' size='340' side='right'caption='[[1kjk]], [[NMR_Ensembles_of_Models | 25 NMR models]]' scene=''>
<StructureSection load='1kjk' size='340' side='right'caption='[[1kjk]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1kjk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_lambda Bacteriophage lambda]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KJK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KJK FirstGlance]. <br>
<table><tr><td colspan='2'>[[1kjk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_Lambda Escherichia virus Lambda]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KJK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KJK FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kjk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kjk OCA], [http://pdbe.org/1kjk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1kjk RCSB], [http://www.ebi.ac.uk/pdbsum/1kjk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1kjk ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kjk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kjk OCA], [https://pdbe.org/1kjk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kjk RCSB], [https://www.ebi.ac.uk/pdbsum/1kjk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kjk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/VINT_LAMBD VINT_LAMBD]] Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome.  
[https://www.uniprot.org/uniprot/VINT_LAMBD VINT_LAMBD] Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Retroviral Integrase|Retroviral Integrase]]
*[[Retroviral integrase 3D structures|Retroviral integrase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacteriophage lambda]]
[[Category: Escherichia virus Lambda]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Clubb, R T]]
[[Category: Clubb RT]]
[[Category: Landy, A]]
[[Category: Landy A]]
[[Category: Sarkar, D]]
[[Category: Sarkar D]]
[[Category: Wojciak, J M]]
[[Category: Wojciak JM]]
[[Category: Dna recombination]]
[[Category: Dna-binding domain]]
[[Category: Integrase]]
[[Category: Three-stranded beta-sheet]]
[[Category: Viral protein]]

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