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<StructureSection load='4i6y' size='340' side='right'caption='[[4i6y]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
<StructureSection load='4i6y' size='340' side='right'caption='[[4i6y]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4i6y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/'pseudomonas_mevalonii' 'pseudomonas mevalonii']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I6Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4I6Y FirstGlance]. <br>
<table><tr><td colspan='2'>[[4i6y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_mevalonii Pseudomonas mevalonii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I6Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4I6Y FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MEV:(R)-MEVALONATE'>MEV</scene>, <scene name='pdbligand=NO2:NITRITE+ION'>NO2</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4i4b|4i4b]], [[4i56|4i56]], [[4i64|4i64]], [[4i6a|4i6a]], [[4i6w|4i6w]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MEV:(R)-MEVALONATE'>MEV</scene>, <scene name='pdbligand=NO2:NITRITE+ION'>NO2</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mvaA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=32044 'Pseudomonas mevalonii'])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4i6y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i6y OCA], [https://pdbe.org/4i6y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4i6y RCSB], [https://www.ebi.ac.uk/pdbsum/4i6y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i6y ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydroxymethylglutaryl-CoA_reductase Hydroxymethylglutaryl-CoA reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.88 1.1.1.88] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4i6y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i6y OCA], [http://pdbe.org/4i6y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4i6y RCSB], [http://www.ebi.ac.uk/pdbsum/4i6y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4i6y ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MVAA_PSEMV MVAA_PSEMV]] P.mevalonii can use mevalonate as sole carbon source. With this enzyme mevalonate is deacetylated to HMG-CoA.  
[https://www.uniprot.org/uniprot/MVAA_PSEMV MVAA_PSEMV] P.mevalonii can use mevalonate as sole carbon source. With this enzyme mevalonate is deacetylated to HMG-CoA.
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[HMG-CoA Reductase|HMG-CoA Reductase]]
*[[HMG-CoA Reductase 3D structures|HMG-CoA Reductase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Pseudomonas mevalonii]]
[[Category: Pseudomonas mevalonii]]
[[Category: Hydroxymethylglutaryl-CoA reductase]]
[[Category: Burgner II JW]]
[[Category: Large Structures]]
[[Category: Critchelow CJ]]
[[Category: Critchelow, C J]]
[[Category: Min J]]
[[Category: II, J W.Burgner]]
[[Category: Rodwell VW]]
[[Category: Min, J]]
[[Category: Schmidt T]]
[[Category: Rodwell, V W]]
[[Category: Stauffacher CV]]
[[Category: Schmidt, T]]
[[Category: Steussy CN]]
[[Category: Stauffacher, C V]]
[[Category: Wrensford LV]]
[[Category: Steussy, C N]]
[[Category: Wrensford, L V]]
[[Category: Oxidoreductase]]

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