1jq2: Difference between revisions

No edit summary
No edit summary
 
(One intermediate revision by the same user not shown)
Line 1: Line 1:


==POTASSIUM CHANNEL (KCSA) OPEN GATE MODEL==
==POTASSIUM CHANNEL (KCSA) OPEN GATE MODEL==
<StructureSection load='1jq2' size='340' side='right'caption='[[1jq2]], [[NMR_Ensembles_of_Models | 50 NMR models]]' scene=''>
<StructureSection load='1jq2' size='340' side='right'caption='[[1jq2]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1jq2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"actinomyces_lividans"_krasil'nikov_et_al._1965 "actinomyces lividans" krasil'nikov et al. 1965]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JQ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JQ2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1jq2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_lividans Streptomyces lividans]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JQ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JQ2 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1jq1|1jq1]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jq2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jq2 OCA], [http://pdbe.org/1jq2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jq2 RCSB], [http://www.ebi.ac.uk/pdbsum/1jq2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1jq2 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jq2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jq2 OCA], [https://pdbe.org/1jq2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jq2 RCSB], [https://www.ebi.ac.uk/pdbsum/1jq2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jq2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/KCSA_STRLI KCSA_STRLI]] Acts as a pH-gated potassium ion channel; changing the cytosolic pH from 7 to 4 opens the channel, although it is not clear if this is the physiological stimulus for channel opening. Monovalent cation preference is K(+) > Rb(+) > NH4(+) >> Na(+) > Li(+).<ref>PMID:7489706</ref>
[https://www.uniprot.org/uniprot/KCSA_STRLI KCSA_STRLI] Acts as a pH-gated potassium ion channel; changing the cytosolic pH from 7 to 4 opens the channel, although it is not clear if this is the physiological stimulus for channel opening. Monovalent cation preference is K(+) > Rb(+) > NH4(+) >> Na(+) > Li(+).<ref>PMID:7489706</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 21: Line 21:
==See Also==
==See Also==
*[[Glutamate receptor (GluA2)|Glutamate receptor (GluA2)]]
*[[Glutamate receptor (GluA2)|Glutamate receptor (GluA2)]]
*[[Potassium Channel|Potassium Channel]]
*[[Potassium channel 3D structures|Potassium channel 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Actinomyces lividans krasil'nikov et al. 1965]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Liu, Y S]]
[[Category: Streptomyces lividans]]
[[Category: Perozo, E]]
[[Category: Liu Y-S]]
[[Category: Sompornpisut, P]]
[[Category: Perozo E]]
[[Category: Integral membrane protein]]
[[Category: Sompornpisut P]]
[[Category: Membrane protein]]
[[Category: Open state]]
[[Category: Potassium channel]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA