1gur: Difference between revisions
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==GURMARIN, A SWEET TASTE-SUPPRESSING POLYPEPTIDE, NMR, 10 STRUCTURES== | ==GURMARIN, A SWEET TASTE-SUPPRESSING POLYPEPTIDE, NMR, 10 STRUCTURES== | ||
<StructureSection load='1gur' size='340' side='right'caption='[[1gur | <StructureSection load='1gur' size='340' side='right'caption='[[1gur]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1gur]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GUR OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[1gur]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gymnema_sylvestre Gymnema sylvestre]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GUR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GUR FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 10 models</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gur FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gur OCA], [https://pdbe.org/1gur PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gur RCSB], [https://www.ebi.ac.uk/pdbsum/1gur PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gur ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/GUR_GYMSY GUR_GYMSY] Suppresses strongly the sweet taste responses in the rat with high specificity to sucrose, glucose, glycine, and saccharin. This effect is reversible, but complete recovery of the suppressed responses required at least 3h. Gurmarin showed no effect or only a very weak effect on the sweet taste sensation in humans. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Gymnema sylvestre]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Aimoto | [[Category: Aimoto S]] | ||
[[Category: Akasaka | [[Category: Akasaka K]] | ||
[[Category: Arai | [[Category: Arai K]] | ||
[[Category: Imoto | [[Category: Imoto T]] | ||
[[Category: Ishima | [[Category: Ishima R]] | ||
[[Category: Morikawa | [[Category: Morikawa S]] | ||
[[Category: Yoshimura | [[Category: Yoshimura S]] | ||