4z1h: Difference between revisions

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 <StructureSection load='4z1h' size='340' side='right'caption='[[4z1h]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4z1h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Z1H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Z1H FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4z1h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Z1H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Z1H FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4KP:8-[(6-IODO-1,3-BENZODIOXOL-5-YL)SULFANYL]-9-[6-(TRIPHENYL-LAMBDA~5~-PHOSPHANYL)HEXYL]-9H-PURIN-6-AMINE'>4KP</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4z1f|4z1f]], [[4z1g|4z1g]], [[4z1i|4z1i]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4KP:8-[(6-IODO-1,3-BENZODIOXOL-5-YL)SULFANYL]-9-[6-(TRIPHENYL-LAMBDA~5~-PHOSPHANYL)HEXYL]-9H-PURIN-6-AMINE'>4KP</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TRAP1, HSP75 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4z1h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4z1h OCA], [https://pdbe.org/4z1h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4z1h RCSB], [https://www.ebi.ac.uk/pdbsum/4z1h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4z1h ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4z1h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4z1h OCA], [http://pdbe.org/4z1h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4z1h RCSB], [http://www.ebi.ac.uk/pdbsum/4z1h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4z1h ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/TRAP1_HUMAN TRAP1_HUMAN]] Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, most likely through stabilization of mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.<ref>PMID:23525905</ref> <ref>PMID:23564345</ref> <ref>PMID:23747254</ref>
+[https://www.uniprot.org/uniprot/TRAP1_HUMAN TRAP1_HUMAN] Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, most likely through stabilization of mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.<ref>PMID:23525905</ref> <ref>PMID:23564345</ref> <ref>PMID:23747254</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
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 ==See Also==
-*[[Heat Shock Proteins|Heat Shock Proteins]]
+*[[Heat Shock Protein structures|Heat Shock Protein structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
 [[Category: Large Structures]]
-[[Category: Kang, B H]]
+[[Category: Kang BH]]
-[[Category: Lee, C]]
+[[Category: Lee C]]
-[[Category: Park, H K]]
+[[Category: Park HK]]
-[[Category: Ryu, J H]]
+[[Category: Ryu JH]]
-[[Category: Chaperone]]
-[[Category: Mitochondrial hsp90]]