6ivu: Difference between revisions

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==Solution structure of the Sigma-anti-sigma factor complex RsgI1N-SigI1C from Clostridium thermocellum==
==Solution structure of the Sigma-anti-sigma factor complex RsgI1N-SigI1C from Clostridium thermocellum==
<StructureSection load='6ivu' size='340' side='right'caption='[[6ivu]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='6ivu' size='340' side='right'caption='[[6ivu]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6ivu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cloth Cloth]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IVU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IVU FirstGlance]. <br>
<table><tr><td colspan='2'>[[6ivu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Acetivibrio_thermocellus_ATCC_27405 Acetivibrio thermocellus ATCC 27405]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IVU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IVU FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6ivs|6ivs]]</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ivu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ivu OCA], [https://pdbe.org/6ivu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ivu RCSB], [https://www.ebi.ac.uk/pdbsum/6ivu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ivu ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cthe_0059 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=203119 CLOTH]), sigI1, Cthe_0058 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=203119 CLOTH])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ivu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ivu OCA], [http://pdbe.org/6ivu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ivu RCSB], [http://www.ebi.ac.uk/pdbsum/6ivu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ivu ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RSGI1_CLOTH RSGI1_CLOTH]] Anti-sigma factor for SigI1. Negatively regulates SigI1 activity through direct interaction (PubMed:20937888). Binding of the polysaccharide substrate to the extracellular C-terminal sensing domain of RsgI1 may induce a conformational change in its N-terminal cytoplasmic region, leading to the release and activation of SigI1 (Probable).<ref>PMID:20937888</ref> <ref>PMID:20937888</ref> [[http://www.uniprot.org/uniprot/SIGI1_CLOTH SIGI1_CLOTH]] Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity). This sigma factor is involved in regulation of cellulosomal genes via an external polysaccharide-sensing mechanism. SigI1 promotes transcription from sigI1 and celS promoters (PubMed:20937888).[HAMAP-Rule:MF_02064]<ref>PMID:20937888</ref> 
[https://www.uniprot.org/uniprot/RSGI1_ACET2 RSGI1_ACET2] Anti-sigma factor for SigI1. Negatively regulates SigI1 activity through direct interaction (PubMed:20937888). Binding of the polysaccharide substrate to the extracellular C-terminal sensing domain of RsgI1 may induce a conformational change in its N-terminal cytoplasmic region, leading to the release and activation of SigI1 (Probable).<ref>PMID:20937888</ref> <ref>PMID:20937888</ref>  
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
<div class="pdbe-citations 6ivu" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6ivu" style="background-color:#fffaf0;"></div>
==See Also==
*[[Sigma factor 3D structures|Sigma factor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Cloth]]
[[Category: Acetivibrio thermocellus ATCC 27405]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Feng, Y]]
[[Category: Feng Y]]
[[Category: Wei, Z]]
[[Category: Wei Z]]
[[Category: Sigma factor]]
[[Category: Transcription]]

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