5cgc: Difference between revisions

<table><tr><td colspan='2'>[[5cgc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CGC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CGC FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.101&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=51D:3-CHLORO-4-FLUORO-5-[6-(1H-PYRAZOL-1-YL)PYRIMIDIN-4-YL]BENZONITRILE'>51D</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5cgc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cgc OCA], [https://pdbe.org/5cgc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5cgc RCSB], [https://www.ebi.ac.uk/pdbsum/5cgc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5cgc ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref> [https://www.uniprot.org/uniprot/GRM5_HUMAN GRM5_HUMAN] Receptor for glutamate. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current.

*[[Metabotropic glutamate receptor 3D structures|Metabotropic glutamate receptor 3D structures]]

[[Category: Escherichia virus T4]]

[[Category: Homo sapiens]]

[[Category: Aves SJ]]

[[Category: Bennett KA]]

[[Category: Christopher JA]]

[[Category: Congreve M]]

[[Category: Dore AS]]

[[Category: Errey JC]]

[[Category: Jazayeri A]]

[[Category: Marshall FH]]

[[Category: Okrasa K]]

[[Category: Serrano-Vega MJ]]

[[Category: Tehan BG]]

[[Category: Wiggin GR]]