6jrl: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
New page: '''Unreleased structure''' The entry 6jrl is ON HOLD Authors: Wei, S., Vavrick, C.J., Guan, H., Robinson, H., Liang, J., Wang, D., Han, Q., Li, J. Description: Crystal structure of Dro...
 
No edit summary
 
(2 intermediate revisions by the same user not shown)
Line 1: Line 1:
'''Unreleased structure'''


The entry 6jrl is ON HOLD
==Crystal structure of Drosophila alpha methyldopa-resistant protein/3,4-dihydroxyphenylacetaldehyde synthase==
 
<StructureSection load='6jrl' size='340' side='right'caption='[[6jrl]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
Authors: Wei, S., Vavrick, C.J., Guan, H., Robinson, H., Liang, J., Wang, D., Han, Q., Li, J.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6jrl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JRL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JRL FirstGlance]. <br>
Description: Crystal structure of Drosophila alpha methyldopa-resistant protein/3,4-dihydroxyphenylacetaldehyde synthase
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
[[Category: Han, Q]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jrl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jrl OCA], [https://pdbe.org/6jrl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jrl RCSB], [https://www.ebi.ac.uk/pdbsum/6jrl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jrl ProSAT]</span></td></tr>
[[Category: Guan, H]]
</table>
[[Category: Liang, J]]
== Function ==
[[Category: Wei, S]]
[https://www.uniprot.org/uniprot/DHAPP_DROME DHAPP_DROME] Catalyzes both the decarboxylation and deamination of L-dopa to 3,4-dihydroxylphenylacetaldehyde (DHPAA) (PubMed:21283636). Probably responsible for the protein cross-linking during the development of flexible cuticles (PubMed:21283636). Participates in catecholamine catabolism (PubMed:21283636).<ref>PMID:21283636</ref>
[[Category: Li, J]]
== References ==
[[Category: Robinson, H]]
<references/>
[[Category: Wang, D]]
__TOC__
[[Category: Vavrick, C.J]]
</StructureSection>
[[Category: Drosophila melanogaster]]
[[Category: Large Structures]]
[[Category: Guan H]]
[[Category: Han Q]]
[[Category: Li J]]
[[Category: Liang J]]
[[Category: Liao C]]
[[Category: Robinson H]]
[[Category: Vavrick CJ]]
[[Category: Wang D]]
[[Category: Wei S]]

Latest revision as of 13:18, 22 November 2023

Crystal structure of Drosophila alpha methyldopa-resistant protein/3,4-dihydroxyphenylacetaldehyde synthaseCrystal structure of Drosophila alpha methyldopa-resistant protein/3,4-dihydroxyphenylacetaldehyde synthase

Structural highlights

6jrl is a 1 chain structure with sequence from Drosophila melanogaster. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

DHAPP_DROME Catalyzes both the decarboxylation and deamination of L-dopa to 3,4-dihydroxylphenylacetaldehyde (DHPAA) (PubMed:21283636). Probably responsible for the protein cross-linking during the development of flexible cuticles (PubMed:21283636). Participates in catecholamine catabolism (PubMed:21283636).[1]

References

  1. ↑ Vavricka C, Han Q, Huang Y, Erickson SM, Harich K, Christensen BM, Li J. From L-dopa to dihydroxyphenylacetaldehyde: a toxic biochemical pathway plays a vital physiological function in insects. PLoS One. 2011 Jan 24;6(1):e16124. doi: 10.1371/journal.pone.0016124. PMID:21283636 doi:http://dx.doi.org/10.1371/journal.pone.0016124

6jrl, resolution 2.20Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=6jrl&oldid=3960340"