4k4c: Difference between revisions

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<StructureSection load='4k4c' size='340' side='right'caption='[[4k4c]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
<StructureSection load='4k4c' size='340' side='right'caption='[[4k4c]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4k4c]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K4C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4K4C FirstGlance]. <br>
<table><tr><td colspan='2'>[[4k4c]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K4C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K4C FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0FQ:PHENACYL+COENZYME+A'>0FQ</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1vh9|1vh9]], [[4k49|4k49]], [[4k4a|4k4a]], [[4k4b|4k4b]], [[4k4d|4k4d]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0FQ:PHENACYL+COENZYME+A'>0FQ</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b0597, entH, JW0589, ybdB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k4c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k4c OCA], [https://pdbe.org/4k4c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k4c RCSB], [https://www.ebi.ac.uk/pdbsum/4k4c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k4c ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k4c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k4c OCA], [http://pdbe.org/4k4c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4k4c RCSB], [http://www.ebi.ac.uk/pdbsum/4k4c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4k4c ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ENTH_ECOLI ENTH_ECOLI]] Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules. Displays esterase activity toward a wide range of substrates, including acyl-CoAs and aryl-CoAs.<ref>PMID:15808744</ref> <ref>PMID:17675380</ref> <ref>PMID:19119850</ref> <ref>PMID:19193103</ref>
[https://www.uniprot.org/uniprot/ENTH_ECOLI ENTH_ECOLI] Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules. Displays esterase activity toward a wide range of substrates, including acyl-CoAs and aryl-CoAs.<ref>PMID:15808744</ref> <ref>PMID:17675380</ref> <ref>PMID:19119850</ref> <ref>PMID:19193103</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Allen, K N]]
[[Category: Allen KN]]
[[Category: Dunaway-Mariano, D]]
[[Category: Dunaway-Mariano D]]
[[Category: Farelli, J D]]
[[Category: Farelli JD]]
[[Category: Ru, W]]
[[Category: Ru W]]
[[Category: Hotdog fold]]
[[Category: Hydrolase]]
[[Category: Thioesterase]]

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