6jp1: Difference between revisions
New page: '''Unreleased structure''' The entry 6jp1 is ON HOLD Authors: Lin, Y.W., Yuan, H. Description: An X-ray structure of met sperm whale F43Y/T67R myoglobin with Tyr-heme double cross-link... |
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==An X-ray structure of met sperm whale F43Y/T67R myoglobin with Tyr-heme double cross-links== | |||
<StructureSection load='6jp1' size='340' side='right'caption='[[6jp1]], [[Resolution|resolution]] 1.99Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6jp1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JP1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JP1 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.99Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jp1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jp1 OCA], [https://pdbe.org/6jp1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jp1 RCSB], [https://www.ebi.ac.uk/pdbsum/6jp1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jp1 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/MYG_PHYMC MYG_PHYMC] Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
The X-ray crystal structure of F43Y/T67R myoglobin revealed unique Tyr-heme double cross-links between Tyr43 and the heme 4-vinyl group, which represents a novel post-translational modification of heme proteins. Moreover, with the feature of a distal His-Arg pair, the designed artificial enzyme exhibited a peroxidase activity comparable to that of native peroxidases, such as the most efficient horseradish peroxidase. | |||
Unique Tyr-heme double cross-links in F43Y/T67R myoglobin: an artificial enzyme with a peroxidase activity comparable to that of native peroxidases.,Liu C, Yuan H, Liao F, Wei CW, Du KJ, Gao SQ, Tan X, Lin YW Chem Commun (Camb). 2019 Jun 11;55(46):6610-6613. doi: 10.1039/c9cc02714a. Epub, 2019 May 23. PMID:31119219<ref>PMID:31119219</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
[[Category: | </div> | ||
[[Category: | <div class="pdbe-citations 6jp1" style="background-color:#fffaf0;"></div> | ||
[[Category: Lin | |||
==See Also== | |||
*[[Myoglobin 3D structures|Myoglobin 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Physeter catodon]] | |||
[[Category: Lin YW]] | |||
[[Category: Yuan H]] | |||