6hoi: Difference between revisions

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==Structure of Beclin1 LIR motif bound to GABARAPL1==
==Structure of Beclin1 LIR motif bound to GABARAPL1==
<StructureSection load='6hoi' size='340' side='right' caption='[[6hoi]], [[Resolution|resolution]] 1.14&Aring;' scene=''>
<StructureSection load='6hoi' size='340' side='right'caption='[[6hoi]], [[Resolution|resolution]] 1.14&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6hoi]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HOI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6HOI FirstGlance]. <br>
<table><tr><td colspan='2'>[[6hoi]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HOI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6HOI FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.14&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6hoi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hoi OCA], [http://pdbe.org/6hoi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6hoi RCSB], [http://www.ebi.ac.uk/pdbsum/6hoi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6hoi ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6hoi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hoi OCA], [https://pdbe.org/6hoi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6hoi RCSB], [https://www.ebi.ac.uk/pdbsum/6hoi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6hoi ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GBRL1_HUMAN GBRL1_HUMAN]] Increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Involved in formation of autophagosomal vacuoles.<ref>PMID:16431922</ref> <ref>PMID:20404487</ref> [[http://www.uniprot.org/uniprot/BECN1_HUMAN BECN1_HUMAN]] Plays a central role in autophagy. Required for the abcission step in cytokinesis. May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.<ref>PMID:20208530</ref> 
[https://www.uniprot.org/uniprot/GBRL1_HUMAN GBRL1_HUMAN] Increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Involved in formation of autophagosomal vacuoles.<ref>PMID:16431922</ref> <ref>PMID:20404487</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6hoi" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6hoi" style="background-color:#fffaf0;"></div>
==See Also==
*[[GABA receptor-associated protein 3D structures|GABA receptor-associated protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bhujbal, Z]]
[[Category: Homo sapiens]]
[[Category: Birgisdottir, A B]]
[[Category: Large Structures]]
[[Category: Evjen, G]]
[[Category: Bhujbal Z]]
[[Category: Johansen, T]]
[[Category: Birgisdottir AB]]
[[Category: Lamark, T]]
[[Category: Evjen G]]
[[Category: Lee, R]]
[[Category: Johansen T]]
[[Category: Mouilleron, S]]
[[Category: Lamark T]]
[[Category: Reilly, N O]]
[[Category: Lee R]]
[[Category: Sjottem, E]]
[[Category: Mouilleron S]]
[[Category: Tooze, S]]
[[Category: O'Reilly N]]
[[Category: Wirth, M]]
[[Category: Sjottem E]]
[[Category: Zhang, W]]
[[Category: Tooze S]]
[[Category: Atg8]]
[[Category: Wirth M]]
[[Category: Autophagy]]
[[Category: Zhang W]]
[[Category: Lir]]
[[Category: Signaling protein]]

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