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==Crystal structure of the PHR domain from human BTBD2 Protein==
==Crystal structure of the PHR domain from human BTBD2 Protein==
<StructureSection load='3no8' size='340' side='right' caption='[[3no8]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='3no8' size='340' side='right'caption='[[3no8]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3no8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NO8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NO8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3no8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NO8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NO8 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BTBD, BTBD2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3no8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3no8 OCA], [http://pdbe.org/3no8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3no8 RCSB], [http://www.ebi.ac.uk/pdbsum/3no8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3no8 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3no8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3no8 OCA], [https://pdbe.org/3no8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3no8 RCSB], [https://www.ebi.ac.uk/pdbsum/3no8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3no8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BTBD2_HUMAN BTBD2_HUMAN]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Atwell, S]]
[[Category: Large Structures]]
[[Category: Bain, K]]
[[Category: Atwell S]]
[[Category: Burley, S K]]
[[Category: Bain K]]
[[Category: Emtage, J S]]
[[Category: Burley SK]]
[[Category: Gheyi, T]]
[[Category: Emtage JS]]
[[Category: Miller, S]]
[[Category: Gheyi T]]
[[Category: Structural genomic]]
[[Category: Miller S]]
[[Category: Rutter, M]]
[[Category: Rutter M]]
[[Category: Sampathkumar, P]]
[[Category: Sampathkumar P]]
[[Category: Sauder, J M]]
[[Category: Sauder JM]]
[[Category: Thompson, D A]]
[[Category: Thompson DA]]
[[Category: Wasserman, S]]
[[Category: Wasserman S]]
[[Category: Btbd1]]
[[Category: Btbd2]]
[[Category: Isomerase regulator]]
[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
[[Category: Pam-highwire-rpm-1 domain]]
[[Category: Phr domain]]
[[Category: PSI, Protein structure initiative]]
[[Category: Toposisomerase regulation]]
[[Category: Transcription]]

Latest revision as of 12:18, 6 September 2023

Crystal structure of the PHR domain from human BTBD2 ProteinCrystal structure of the PHR domain from human BTBD2 Protein

Structural highlights

3no8 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

BTBD2_HUMAN

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

3no8, resolution 2.20Å

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OCA
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