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==Aquifex aeolicus LpxC complex with ACHN-975==
==Aquifex aeolicus LpxC complex with ACHN-975==
<StructureSection load='6ih0' size='340' side='right' caption='[[6ih0]], [[Resolution|resolution]] 1.21&Aring;' scene=''>
<StructureSection load='6ih0' size='340' side='right'caption='[[6ih0]], [[Resolution|resolution]] 1.21&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6ih0]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IH0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IH0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[6ih0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus_VF5 Aquifex aeolicus VF5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IH0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IH0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A5F:N-[(2S)-3-azanyl-3-methyl-1-(oxidanylamino)-1-oxidanylidene-butan-2-yl]-4-[4-[(1R,2R)-2-(hydroxymethyl)cyclopropyl]buta-1,3-diynyl]benzamide'>A5F</scene>, <scene name='pdbligand=A5U:methyl+(2S)-2-azanyl-3-methyl-3-[(2-methylpropan-2-yl)oxycarbonylamino]butanoate'>A5U</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.21&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-3-O-acyl-N-acetylglucosamine_deacetylase UDP-3-O-acyl-N-acetylglucosamine deacetylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.108 3.5.1.108] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A5F:N-[(2S)-3-azanyl-3-methyl-1-(oxidanylamino)-1-oxidanylidene-butan-2-yl]-4-[4-[(1R,2R)-2-(hydroxymethyl)cyclopropyl]buta+-1,3-diynyl]benzamide'>A5F</scene>, <scene name='pdbligand=A5U:methyl+(2S)-2-azanyl-3-methyl-3-[(2-methylpropan-2-yl)oxycarbonylamino]butanoate'>A5U</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ih0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ih0 OCA], [http://pdbe.org/6ih0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ih0 RCSB], [http://www.ebi.ac.uk/pdbsum/6ih0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ih0 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ih0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ih0 OCA], [https://pdbe.org/6ih0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ih0 RCSB], [https://www.ebi.ac.uk/pdbsum/6ih0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ih0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/LPXC_AQUAE LPXC_AQUAE]] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity).  
[https://www.uniprot.org/uniprot/LPXC_AQUAE LPXC_AQUAE] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity).
 
==See Also==
*[[UDP-3-O-acyl-N-acetylglucosamine deacetylase|UDP-3-O-acyl-N-acetylglucosamine deacetylase]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: UDP-3-O-acyl-N-acetylglucosamine deacetylase]]
[[Category: Aquifex aeolicus VF5]]
[[Category: Fan, S]]
[[Category: Large Structures]]
[[Category: Jin, Y Y]]
[[Category: Fan S]]
[[Category: Li, D Y]]
[[Category: Jin YY]]
[[Category: Lv, G X]]
[[Category: Li DY]]
[[Category: Wu, G T]]
[[Category: Lv GX]]
[[Category: Yang, Z Y]]
[[Category: Wu GT]]
[[Category: Zhang, C]]
[[Category: Yang ZY]]
[[Category: Antibiotic]]
[[Category: Zhang C]]
[[Category: Complex]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Inhibitor]]

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