3cbt: Difference between revisions

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[[Image:3cbt.jpg|left|200px]]


{{Structure
==Crystal structure of SC4828, a unique phosphatase from Streptomyces coelicolor==
|PDB= 3cbt |SIZE=350|CAPTION= <scene name='initialview01'>3cbt</scene>, resolution 1.70&Aring;
<StructureSection load='3cbt' size='340' side='right'caption='[[3cbt]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
|SITE= <scene name='pdbsite=AC1:Mg+Binding+Site+For+Residue+A+301'>AC1</scene>, <scene name='pdbsite=AC2:Na+Binding+Site+For+Residue+A+401'>AC2</scene>, <scene name='pdbsite=AC3:Na+Binding+Site+For+Residue+A+410'>AC3</scene> and <scene name='pdbsite=AC4:Na+Binding+Site+For+Residue+A+420'>AC4</scene>
== Structural highlights ==
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>
<table><tr><td colspan='2'>[[3cbt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Strco Strco]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3bxt 3bxt]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CBT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CBT FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/5'-nucleotidase 5'-nucleotidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.5 3.1.3.5] </span>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
|GENE= SCO5041, SCK7.14, SCK7.14c, gi:21223414 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2 Bacteria])
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam04167 DUF402]</span>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SCO5041, SCK7.14, SCK7.14c, gi:21223414 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=100226 STRCO])</td></tr>
|RELATEDENTRY=
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/5'-nucleotidase 5'-nucleotidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.5 3.1.3.5] </span></td></tr>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cbt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cbt OCA], [http://www.ebi.ac.uk/pdbsum/3cbt PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3cbt RCSB]</span>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cbt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cbt OCA], [https://pdbe.org/3cbt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cbt RCSB], [https://www.ebi.ac.uk/pdbsum/3cbt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cbt ProSAT], [https://www.topsan.org/Proteins/MCSG/3cbt TOPSAN]</span></td></tr>
}}
</table>
 
== Evolutionary Conservation ==
'''Crystal structure of SC4828, a unique phosphatase from Streptomyces coelicolor'''
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
 
  <jmolCheckbox>
==About this Structure==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cb/3cbt_consurf.spt"</scriptWhenChecked>
3CBT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacteria Bacteria]. This structure supersedes the now removed PDB entry 3BXT. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CBT OCA].  
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cbt ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: 5'-nucleotidase]]
[[Category: 5'-nucleotidase]]
[[Category: Bacteria]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Strco]]
[[Category: Chang, C.]]
[[Category: Chang, C]]
[[Category: Edwards, A M.]]
[[Category: Edwards, A M]]
[[Category: Joachimiak, A.]]
[[Category: Joachimiak, A]]
[[Category: MCSG, Midwest Center for Structural Genomics.]]
[[Category: Structural genomic]]
[[Category: Savchenko, A.]]
[[Category: Savchenko, A]]
[[Category: Singer, A U.]]
[[Category: Singer, A U]]
[[Category: Xu, X.]]
[[Category: Xu, X]]
[[Category: Yakunin, A F.]]
[[Category: Yakunin, A F]]
[[Category: Zheng, H.]]
[[Category: Zheng, H]]
[[Category: crystal structure]]
[[Category: Duf402]]
[[Category: duf402]]
[[Category: Hydrolase]]
[[Category: hydrolase]]
[[Category: Mcsg]]
[[Category: mcsg]]
[[Category: PSI, Protein structure initiative]]
[[Category: midwest center for structural genomic]]
[[Category: Streptomyces unusual phosphatase]]
[[Category: protein structure initiative]]
[[Category: psi-2]]
[[Category: streptomyces unusual phosphatase]]
[[Category: structural genomic]]
 
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