3hcc: Difference between revisions

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OCA

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 ==Crystal Structure of hPNMT in Complex With anti-9-amino-5-(trifluromethyl) benzonorbornene and AdoHcy==
-<StructureSection load='3hcc' size='340' side='right' caption='[[3hcc]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
+<StructureSection load='3hcc' size='340' side='right'caption='[[3hcc]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3hcc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HCC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HCC FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3hcc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HCC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HCC FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LT3:(1S,4R,9S)-5-(TRIFLUOROMETHYL)-1,2,3,4-TETRAHYDRO-1,4-METHANONAPHTHALEN-9-AMINE'>LT3</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1hnn|1hnn]], [[1n7i|1n7i]], [[1n7j|1n7j]], [[1yz3|1yz3]], [[2an3|2an3]], [[2an5|2an5]], [[2an4|2an4]], [[2g70|2g70]], [[2ony|2ony]], [[2g71|2g71]], [[2g72|2g72]], [[2onz|2onz]], [[2obf|2obf]], [[2opb|2opb]], [[2g8n|2g8n]], [[3hca|3hca]], [[3hcb|3hcb]], [[3hcd|3hcd]], [[3hce|3hce]], [[3hcf|3hcf]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LT3:(1S,4R,9S)-5-(TRIFLUOROMETHYL)-1,2,3,4-TETRAHYDRO-1,4-METHANONAPHTHALEN-9-AMINE'>LT3</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PNMT, PENT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hcc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hcc OCA], [https://pdbe.org/3hcc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hcc RCSB], [https://www.ebi.ac.uk/pdbsum/3hcc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hcc ProSAT]</span></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phenylethanolamine_N-methyltransferase Phenylethanolamine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.28 2.1.1.28] </span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hcc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hcc OCA], [http://pdbe.org/3hcc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hcc RCSB], [http://www.ebi.ac.uk/pdbsum/3hcc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hcc ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/PNMT_HUMAN PNMT_HUMAN]] Converts noradrenaline to adrenaline.
+[https://www.uniprot.org/uniprot/PNMT_HUMAN PNMT_HUMAN] Converts noradrenaline to adrenaline.
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 17: / Line 15: @@
    <jmolCheckbox>
      <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hc/3hcc_consurf.spt"</scriptWhenChecked>
-     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
@@ Line 38: / Line 36: @@
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
-[[Category: Phenylethanolamine N-methyltransferase]]
+[[Category: Large Structures]]
-[[Category: Drinkwater, N]]
+[[Category: Drinkwater N]]
-[[Category: Gee, C L]]
+[[Category: Gee CL]]
-[[Category: Martin, J L]]
+[[Category: Martin JL]]
-[[Category: Puri, M]]
+[[Category: Puri M]]
-[[Category: Catecholamine biosynthesis]]
-[[Category: Methyltransferase]]
-[[Category: Polymorphism]]
-[[Category: S-adenosyl-l-methionine]]
-[[Category: Transferase]]