3hps: Difference between revisions

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 ==Crystal structure of Mycobacterium tuberculosis LeuA complexed with ketoisocaproate (KIC)==
-<StructureSection load='3hps' size='340' side='right' caption='[[3hps]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
+<StructureSection load='3hps' size='340' side='right'caption='[[3hps]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3hps]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HPS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HPS FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3hps]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HPS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HPS FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=COI:2-OXO-4-METHYLPENTANOIC+ACID'>COI</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=LEU:LEUCINE'>LEU</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1sr9|1sr9]], [[3fig|3fig]], [[3hpx|3hpx]], [[3hpz|3hpz]], [[3hq1|3hq1]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COI:2-OXO-4-METHYLPENTANOIC+ACID'>COI</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=LEU:LEUCINE'>LEU</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">leuA, MT3813, MTV025.058, Rv3710 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hps FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hps OCA], [https://pdbe.org/3hps PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hps RCSB], [https://www.ebi.ac.uk/pdbsum/3hps PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hps ProSAT]</span></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-isopropylmalate_synthase 2-isopropylmalate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.3.13 2.3.3.13] </span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hps FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hps OCA], [http://pdbe.org/3hps PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hps RCSB], [http://www.ebi.ac.uk/pdbsum/3hps PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hps ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/LEU1_MYCTU LEU1_MYCTU]] Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity).
+[https://www.uniprot.org/uniprot/LEU1_MYCTU LEU1_MYCTU] Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity).
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 24: / Line 22: @@
 ==See Also==
-*[[2-isopropylmalate synthase|2-isopropylmalate synthase]]
+*[[2-isopropylmalate synthase 3D structures|2-isopropylmalate synthase 3D structures]]
 __TOC__
 </StructureSection>
-[[Category: 2-isopropylmalate synthase]]
+[[Category: Large Structures]]
-[[Category: Myctu]]
+[[Category: Mycobacterium tuberculosis H37Rv]]
-[[Category: Baker, E N]]
+[[Category: Baker EN]]
-[[Category: Koon, N]]
+[[Category: Koon N]]
-[[Category: Squire, C J]]
+[[Category: Squire CJ]]
-[[Category: Amino-acid biosynthesis]]
-[[Category: Branched-chain amino acid biosynthesis]]
-[[Category: Enzyme]]
-[[Category: Leua]]
-[[Category: Leucine biosynthesis]]
-[[Category: Mycobacterium tuberculosis]]
-[[Category: Regulatory domain]]
-[[Category: Substrate]]
-[[Category: Tim barrel]]
-[[Category: Transferase]]