3fv7: Difference between revisions

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==OXA-24 beta-lactamase complex with SA4-44 inhibitor==
==OXA-24 beta-lactamase complex with SA4-44 inhibitor==
<StructureSection load='3fv7' size='340' side='right' caption='[[3fv7]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='3fv7' size='340' side='right'caption='[[3fv7]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3fv7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aciba Aciba]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FV7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FV7 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3fv7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Acinetobacter_baumannii Acinetobacter baumannii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FV7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FV7 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MXS:(2S)-2-[[2-METHANOYL-7-(METHOXYCARBONYLAMINO)INDOLIZIN-3-YL]AMINO]-3-METHYL-3-SULFINO-BUTANOIC+ACID'>MXS</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene>, <scene name='pdbligand=MXS:(2S)-2-[[2-METHANOYL-7-(METHOXYCARBONYLAMINO)INDOLIZIN-3-YL]AMINO]-3-METHYL-3-SULFINO-BUTANOIC+ACID'>MXS</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">blaOXA-33, bla-OXA-40, oxa-24, oxa40 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=470 ACIBA])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fv7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fv7 OCA], [https://pdbe.org/3fv7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fv7 RCSB], [https://www.ebi.ac.uk/pdbsum/3fv7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fv7 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fv7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fv7 OCA], [http://pdbe.org/3fv7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fv7 RCSB], [http://www.ebi.ac.uk/pdbsum/3fv7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3fv7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q8RLA6_ACIBA Q8RLA6_ACIBA]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Beta-lactamase|Beta-lactamase]]
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Aciba]]
[[Category: Acinetobacter baumannii]]
[[Category: Beta-lactamase]]
[[Category: Large Structures]]
[[Category: Akker, F Van den]]
[[Category: Beceiro A]]
[[Category: Beceiro, A]]
[[Category: Bethel CR]]
[[Category: Bethel, C R]]
[[Category: Bonomo RA]]
[[Category: Bonomo, R A]]
[[Category: Bou G]]
[[Category: Bou, G]]
[[Category: Buynak JD]]
[[Category: Buynak, J D]]
[[Category: Distler AM]]
[[Category: Distler, A M]]
[[Category: Drawz SM]]
[[Category: Drawz, S M]]
[[Category: Kalp M]]
[[Category: Kalp, M]]
[[Category: Pagadala SR]]
[[Category: Pagadala, S R]]
[[Category: Romero A]]
[[Category: Romero, A]]
[[Category: Sampson JM]]
[[Category: Sampson, J M]]
[[Category: Santillana E]]
[[Category: Santillana, E]]
[[Category: Sheri A]]
[[Category: Sheri, A]]
[[Category: Van den Akker F]]
[[Category: B-lactamase]]
[[Category: Carbapenem]]
[[Category: Enzyme mechanism]]
[[Category: Hydrolase]]
[[Category: Inhibitor]]

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