2ogf: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older edit
No edit summary
No edit summary
 
(One intermediate revision by the same user not shown)
Line 1: Line 1:


==Crystal structure of protein MJ0408 from Methanococcus jannaschii, Pfam DUF372==
==Crystal structure of protein MJ0408 from Methanococcus jannaschii, Pfam DUF372==
<StructureSection load='2ogf' size='340' side='right' caption='[[2ogf]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
<StructureSection load='2ogf' size='340' side='right'caption='[[2ogf]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ogf]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43067 Atcc 43067]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OGF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OGF FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ogf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OGF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OGF FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=OXG:8-OXOGUANINE'>OXG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.89&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=OXG:8-OXOGUANINE'>OXG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MJ0408 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 ATCC 43067])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ogf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ogf OCA], [https://pdbe.org/2ogf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ogf RCSB], [https://www.ebi.ac.uk/pdbsum/2ogf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ogf ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2ogf TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ogf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ogf OCA], [http://pdbe.org/2ogf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ogf RCSB], [http://www.ebi.ac.uk/pdbsum/2ogf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ogf ProSAT], [http://www.topsan.org/Proteins/NYSGXRC/2ogf TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MPTD_METJA MPTD_METJA]] Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).[HAMAP-Rule:MF_02130]<ref>PMID:22931285</ref>
[https://www.uniprot.org/uniprot/MPTD_METJA MPTD_METJA] Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).[HAMAP-Rule:MF_02130]<ref>PMID:22931285</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 25: Line 24:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 43067]]
[[Category: Large Structures]]
[[Category: Almo, S C]]
[[Category: Methanocaldococcus jannaschii]]
[[Category: Burley, S K]]
[[Category: Almo SC]]
[[Category: Structural genomic]]
[[Category: Burley SK]]
[[Category: Ramagopal, U A]]
[[Category: Ramagopal UA]]
[[Category: Sauder, J M]]
[[Category: Sauder JM]]
[[Category: Toro, R]]
[[Category: Toro R]]
[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
[[Category: PSI, Protein structure initiative]]
[[Category: Unknown function]]

Latest revision as of 13:38, 30 August 2023

Crystal structure of protein MJ0408 from Methanococcus jannaschii, Pfam DUF372Crystal structure of protein MJ0408 from Methanococcus jannaschii, Pfam DUF372

Structural highlights

2ogf is a 4 chain structure with sequence from Methanocaldococcus jannaschii. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.89Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

MPTD_METJA Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).[HAMAP-Rule:MF_02130][1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ de Crecy-Lagard V, Phillips G, Grochowski LL, El Yacoubi B, Jenney F, Adams MW, Murzin AG, White RH. Comparative genomics guided discovery of two missing archaeal enzyme families involved in the biosynthesis of the pterin moiety of tetrahydromethanopterin and tetrahydrofolate. ACS Chem Biol. 2012 Nov 16;7(11):1807-16. doi: 10.1021/cb300342u. Epub 2012 Sep, 7. PMID:22931285 doi:http://dx.doi.org/10.1021/cb300342u

2ogf, resolution 1.89Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=2ogf&oldid=3852856"