3bb3: Difference between revisions

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==Crystal structure of Toc33 from Arabidopsis thaliana in complex with GDP and Mg2+==
==Crystal structure of Toc33 from Arabidopsis thaliana in complex with GDP and Mg2+==
<StructureSection load='3bb3' size='340' side='right' caption='[[3bb3]], [[Resolution|resolution]] 2.94&Aring;' scene=''>
<StructureSection load='3bb3' size='340' side='right'caption='[[3bb3]], [[Resolution|resolution]] 2.94&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3bb3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BB3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BB3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3bb3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BB3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BB3 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.94&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3bb1|3bb1]], [[3bb4|3bb4]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">T7I23.11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bb3 OCA], [https://pdbe.org/3bb3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bb3 RCSB], [https://www.ebi.ac.uk/pdbsum/3bb3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bb3 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bb3 OCA], [http://pdbe.org/3bb3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3bb3 RCSB], [http://www.ebi.ac.uk/pdbsum/3bb3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3bb3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/TOC33_ARATH TOC33_ARATH]] GTPase involved in protein precursor import into chloroplasts. Seems to recognize chloroplast-destined precursor proteins and regulate their presentation to the translocation channel through GTP hydrolysis. Binds GTP, GDP, XTP, but not ATP. Probably specialized in the import of nuclear encoded photosynthetic preproteins from the cytoplasm to the chloroplast, especially during early development stages.<ref>PMID:11553737</ref> <ref>PMID:12741849</ref> <ref>PMID:12782294</ref> <ref>PMID:12869544</ref> <ref>PMID:12951325</ref> <ref>PMID:12897258</ref> <ref>PMID:15053763</ref> <ref>PMID:16412428</ref> <ref>PMID:16435266</ref> <ref>PMID:18054337</ref>
[https://www.uniprot.org/uniprot/TOC33_ARATH TOC33_ARATH] GTPase involved in protein precursor import into chloroplasts. Seems to recognize chloroplast-destined precursor proteins and regulate their presentation to the translocation channel through GTP hydrolysis. Binds GTP, GDP, XTP, but not ATP. Probably specialized in the import of nuclear encoded photosynthetic preproteins from the cytoplasm to the chloroplast, especially during early development stages.<ref>PMID:11553737</ref> <ref>PMID:12741849</ref> <ref>PMID:12782294</ref> <ref>PMID:12869544</ref> <ref>PMID:12951325</ref> <ref>PMID:12897258</ref> <ref>PMID:15053763</ref> <ref>PMID:16412428</ref> <ref>PMID:16435266</ref> <ref>PMID:18054337</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Arath]]
[[Category: Arabidopsis thaliana]]
[[Category: Koenig, P]]
[[Category: Large Structures]]
[[Category: Schleiff, E]]
[[Category: Koenig P]]
[[Category: Sinning, I]]
[[Category: Schleiff E]]
[[Category: Tews, I]]
[[Category: Sinning I]]
[[Category: Chloroplast import]]
[[Category: Tews I]]
[[Category: Gtp-binding]]
[[Category: Gtpase domain]]
[[Category: Hydrolase]]
[[Category: Membrane]]
[[Category: Nucleotide-binding]]
[[Category: Outer membrane]]
[[Category: Protein transport]]
[[Category: Rossmann fold]]
[[Category: Transmembrane]]
[[Category: Transport]]

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