2qqe: Difference between revisions

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[[Image:2qqe.gif|left|200px]]


{{Structure
==Thymidine Kinase from Thermotoga Maritima in complex with Thymidine==
|PDB= 2qqe |SIZE=350|CAPTION= <scene name='initialview01'>2qqe</scene>, resolution 1.90&Aring;
<StructureSection load='2qqe' size='340' side='right'caption='[[2qqe]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
|SITE=
== Structural highlights ==
|LIGAND= <scene name='pdbligand=THM:THYMIDINE'>THM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
<table><tr><td colspan='2'>[[2qqe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QQE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QQE FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidine_kinase Thymidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.21 2.7.1.21] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
|GENE= tdk ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 Thermotoga maritima])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=THM:THYMIDINE'>THM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qqe OCA], [https://pdbe.org/2qqe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qqe RCSB], [https://www.ebi.ac.uk/pdbsum/2qqe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qqe ProSAT]</span></td></tr>
|RELATEDENTRY=[[2qpo|2QPO]], [[2qq0|2QQ0]]
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qqe OCA], [http://www.ebi.ac.uk/pdbsum/2qqe PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2qqe RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/KITH_THEMA KITH_THEMA]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qq/2qqe_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qqe ConSurf].
<div style="clear:both"></div>


'''Thymidine Kinase from Thermotoga Maritima in complex with Thymidine'''
==See Also==
 
*[[Thymidine kinase 3D structures|Thymidine kinase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2QQE is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QQE OCA].
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
[[Category: Thymidine kinase]]
[[Category: Konrad M]]
[[Category: Konrad, M.]]
[[Category: Lavie A]]
[[Category: Lavie, A.]]
[[Category: Lichter J]]
[[Category: Lichter, J.]]
[[Category: Lutz S]]
[[Category: Lutz, S.]]
[[Category: Segura-Pena D]]
[[Category: Segura-Pena, D.]]
[[Category: Trani M]]
[[Category: Trani, M.]]
[[Category: atp-binding]]
[[Category: close conformation]]
[[Category: cytoplasm]]
[[Category: dna synthesis]]
[[Category: kinase]]
[[Category: nucleotide-binding]]
[[Category: tmtk in complex with thymidine]]
[[Category: transferase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:52:05 2008''

Latest revision as of 12:17, 21 February 2024

Thymidine Kinase from Thermotoga Maritima in complex with ThymidineThymidine Kinase from Thermotoga Maritima in complex with Thymidine

Structural highlights

2qqe is a 2 chain structure with sequence from Thermotoga maritima. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.9Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

KITH_THEMA

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2qqe, resolution 1.90Å

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