6hp8: Difference between revisions
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New page: '''Unreleased structure''' The entry 6hp8 is ON HOLD Authors: Ross, B.H., Huber, R. Description: DPP8 bound to Val-BoroPro Category: Unreleased Structures Category: Ross, B.H [... |
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==Crystal structure of DPP8 in complex with Val-BoroPro== | |||
<StructureSection load='6hp8' size='340' side='right'caption='[[6hp8]], [[Resolution|resolution]] 2.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6hp8]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HP8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6HP8 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GK2:[(2~{R})-1-[(2~{R})-2-azanyl-3-methyl-butanoyl]pyrrolidin-2-yl]boronic+acid'>GK2</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dipeptidyl-peptidase_IV Dipeptidyl-peptidase IV], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.14.5 3.4.14.5] </span></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6hp8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hp8 OCA], [http://pdbe.org/6hp8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6hp8 RCSB], [http://www.ebi.ac.uk/pdbsum/6hp8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6hp8 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/DPP8_HUMAN DPP8_HUMAN]] Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2. May play a role in T-cell activation and immune function.<ref>PMID:11012666</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Dipeptidyl-peptidase IV]] | |||
[[Category: Large Structures]] | |||
[[Category: Huber, R]] | [[Category: Huber, R]] | ||
[[Category: Ross, B H]] | |||
[[Category: Dpp8]] | |||
[[Category: Hydrolase]] | |||
[[Category: Protease]] | |||
[[Category: Val-boropro]] | |||
Latest revision as of 09:15, 31 July 2019
Crystal structure of DPP8 in complex with Val-BoroProCrystal structure of DPP8 in complex with Val-BoroPro
Structural highlights
Function[DPP8_HUMAN] Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2. May play a role in T-cell activation and immune function.[1] References |
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