6c74: Difference between revisions

No edit summary
No edit summary
 
(One intermediate revision by the same user not shown)
Line 1: Line 1:


==Crystal Structure of Murine CD300lf in complex with phosphocholine==
==Crystal Structure of Murine CD300lf in complex with phosphocholine==
<StructureSection load='6c74' size='340' side='right' caption='[[6c74]], [[Resolution|resolution]] 1.36&Aring;' scene=''>
<StructureSection load='6c74' size='340' side='right'caption='[[6c74]], [[Resolution|resolution]] 1.36&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6c74]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6C74 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6C74 FirstGlance]. <br>
<table><tr><td colspan='2'>[[6c74]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6C74 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6C74 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PC:PHOSPHOCHOLINE'>PC</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.358&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ffl|5ffl]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PC:PHOSPHOCHOLINE'>PC</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cd300lf, Clm1, Lmir3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6c74 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6c74 OCA], [https://pdbe.org/6c74 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6c74 RCSB], [https://www.ebi.ac.uk/pdbsum/6c74 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6c74 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6c74 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6c74 OCA], [http://pdbe.org/6c74 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6c74 RCSB], [http://www.ebi.ac.uk/pdbsum/6c74 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6c74 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CLM1_MOUSE CLM1_MOUSE]] Acts as an inhibitory receptor for myeloid cells and mast cells. Inhibits osteoclast formation. Induces macrophage cell death upon engagement.<ref>PMID:14662855</ref> <ref>PMID:17438331</ref> <ref>PMID:18097021</ref>
[https://www.uniprot.org/uniprot/CLM1_MOUSE CLM1_MOUSE] Acts as an inhibitory receptor for myeloid cells and mast cells. Inhibits osteoclast formation. Induces macrophage cell death upon engagement.<ref>PMID:14662855</ref> <ref>PMID:17438331</ref> <ref>PMID:18097021</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 24: Line 23:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Lk3 transgenic mice]]
[[Category: Large Structures]]
[[Category: Fremont, D H]]
[[Category: Mus musculus]]
[[Category: Nelson, C A]]
[[Category: Fremont DH]]
[[Category: Cd300lf]]
[[Category: Nelson CA]]
[[Category: Clm-1]]
[[Category: Clm1]]
[[Category: Cmrf-35-like molecule-1]]
[[Category: Dir2]]
[[Category: Igv-like domain]]
[[Category: Irem1]]
[[Category: Lipid binding protein]]
[[Category: Lmir3]]
[[Category: Myeloid receptor]]
[[Category: Pigr3. igsf13]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA