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==Crystal structure of fluorophore-labeled beta-lactamase PenP in complex with cefotaxime==
==Crystal structure of fluorophore-labeled beta-lactamase PenP in complex with cefotaxime==
<StructureSection load='3sh9' size='340' side='right' caption='[[3sh9]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='3sh9' size='340' side='right'caption='[[3sh9]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3sh9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"clostridium_licheniforme"_weigmann_1898 "clostridium licheniforme" weigmann 1898]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3kgn 3kgn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SH9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SH9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3sh9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_licheniformis Bacillus licheniformis]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3kgn 3kgn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SH9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SH9 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BB0:1-[6-(DIMETHYLAMINO)NAPHTHALEN-2-YL]ETHANONE'>BB0</scene>, <scene name='pdbligand=CEF:CEFOTAXIME,+C3+CLEAVED,+OPEN,+BOUND+FORM'>CEF</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3sh7|3sh7]], [[3sh8|3sh8]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BB0:1-[6-(DIMETHYLAMINO)NAPHTHALEN-2-YL]ETHANONE'>BB0</scene>, <scene name='pdbligand=CEF:CEFOTAXIME,+C3+CLEAVED,+OPEN,+BOUND+FORM'>CEF</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">penP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1402 "Clostridium licheniforme" Weigmann 1898])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sh9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sh9 OCA], [https://pdbe.org/3sh9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sh9 RCSB], [https://www.ebi.ac.uk/pdbsum/3sh9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sh9 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3sh9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sh9 OCA], [http://pdbe.org/3sh9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3sh9 RCSB], [http://www.ebi.ac.uk/pdbsum/3sh9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3sh9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BLAC_BACLI BLAC_BACLI]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Beta-lactamase|Beta-lactamase]]
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Clostridium licheniforme weigmann 1898]]
[[Category: Bacillus licheniformis]]
[[Category: Beta-lactamase]]
[[Category: Large Structures]]
[[Category: Leung, Y C]]
[[Category: Leung Y-C]]
[[Category: Wong, W T]]
[[Category: Wong W-T]]
[[Category: Zhao, Y X]]
[[Category: Zhao Y-X]]
[[Category: Cefotaxime]]
[[Category: Fluorophore]]
[[Category: Hydrolase-antibiotic complex]]
[[Category: Penp]]

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