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==The 20S supercomplex engaging the SNAP-25 N-terminus (class 2)== | ==The 20S supercomplex engaging the SNAP-25 N-terminus (class 2)== | ||
< | <SX load='6mdn' size='340' side='right' viewer='molstar' caption='[[6mdn]], [[Resolution|resolution]] 4.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6mdn]] is a 11 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MDN OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[6mdn]] is a 11 chain structure with sequence from [https://en.wikipedia.org/wiki/Cricetulus_griseus Cricetulus griseus] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MDN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6MDN FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.4Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6mdn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mdn OCA], [https://pdbe.org/6mdn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6mdn RCSB], [https://www.ebi.ac.uk/pdbsum/6mdn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6mdn ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/NSF_CRIGR NSF_CRIGR] Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seem to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling. | ||
==See Also== | |||
*[[ATPase 3D structures|ATPase 3D structures]] | |||
*[[Synaptosomal-associated protein|Synaptosomal-associated protein]] | |||
*[[Syntaxin 3D structures|Syntaxin 3D structures]] | |||
*[[Vesicle-associated membrane protein|Vesicle-associated membrane protein]] | |||
__TOC__ | __TOC__ | ||
</ | </SX> | ||
[[Category: | [[Category: Cricetulus griseus]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Rattus norvegicus]] | ||
[[Category: | [[Category: Brunger AT]] | ||
[[Category: | [[Category: White KI]] | ||
[[Category: | [[Category: Zhao M]] | ||
Latest revision as of 17:42, 13 March 2024
The 20S supercomplex engaging the SNAP-25 N-terminus (class 2)The 20S supercomplex engaging the SNAP-25 N-terminus (class 2)
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