2qjm: Difference between revisions
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==Crystal structure of the K271E mutant of Mannonate dehydratase from Novosphingobium aromaticivorans complexed with Mg and D-mannonate== | ==Crystal structure of the K271E mutant of Mannonate dehydratase from Novosphingobium aromaticivorans complexed with Mg and D-mannonate== | ||
<StructureSection load='2qjm' size='340' side='right' caption='[[2qjm]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='2qjm' size='340' side='right'caption='[[2qjm]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2qjm]] is a 4 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2qjm]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Novosphingobium_aromaticivorans Novosphingobium aromaticivorans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QJM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QJM FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CS2:D-MANNONIC+ACID'>CS2</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qjm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qjm OCA], [https://pdbe.org/2qjm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qjm RCSB], [https://www.ebi.ac.uk/pdbsum/2qjm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qjm ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/MAND_NOVAD MAND_NOVAD] Catalyzes the dehydration of D-mannonate. Has no detectable activity with a panel of 70 other acid sugars (in vitro).<ref>PMID:17944491</ref> <ref>PMID:24697546</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
*[[Mandelate racemase/muconate lactonizing enzyme|Mandelate racemase/muconate lactonizing enzyme]] | *[[Mandelate racemase/muconate lactonizing enzyme|Mandelate racemase/muconate lactonizing enzyme]] | ||
*[[Mandelate racemase/muconate lactonizing enzyme 3D structures|Mandelate racemase/muconate lactonizing enzyme 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Novosphingobium aromaticivorans]] | ||
[[Category: | [[Category: Almo SC]] | ||
[[Category: Fedorov | [[Category: Fedorov AA]] | ||
[[Category: | [[Category: Fedorov EV]] | ||
[[Category: | [[Category: Gerlt JA]] | ||
[[Category: | [[Category: Rakus JF]] | ||
[[Category: | [[Category: Vick JE]] | ||