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==Crystal Structure of staphyloccocal nuclease VIAGAN/E75A variant at cryogenic temperature==
==Crystal Structure of staphyloccocal nuclease VIAGAN/E75A variant at cryogenic temperature==
<StructureSection load='2rdf' size='340' side='right' caption='[[2rdf]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
<StructureSection load='2rdf' size='340' side='right'caption='[[2rdf]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2rdf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RDF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RDF FirstGlance]. <br>
<table><tr><td colspan='2'>[[2rdf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RDF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RDF FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.01&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">nuc ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Micrococcal_nuclease Micrococcal nuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.31.1 3.1.31.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rdf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rdf OCA], [https://pdbe.org/2rdf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rdf RCSB], [https://www.ebi.ac.uk/pdbsum/2rdf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rdf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rdf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rdf OCA], [http://pdbe.org/2rdf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2rdf RCSB], [http://www.ebi.ac.uk/pdbsum/2rdf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2rdf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/NUC_STAAU NUC_STAAU]] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.  
[https://www.uniprot.org/uniprot/NUC_STAAU NUC_STAAU] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Staphylococcal nuclease|Staphylococcal nuclease]]
*[[Staphylococcal nuclease 3D structures|Staphylococcal nuclease 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Micrococcal nuclease]]
[[Category: Large Structures]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
[[Category: Baran, K]]
[[Category: Baran K]]
[[Category: Garcia-Moreno, B E]]
[[Category: Garcia-Moreno BE]]
[[Category: Schlessman, J L]]
[[Category: Schlessman JL]]
[[Category: Calcium]]
[[Category: Endonuclease]]
[[Category: Histidine]]
[[Category: Hydrolase]]
[[Category: Hyperstable variant]]
[[Category: Long-range interaction]]
[[Category: Membrane]]
[[Category: Metal-binding]]
[[Category: Secreted]]
[[Category: Staphylococcal nuclease]]
[[Category: Zymogen]]

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